Download full-text PDF

Source
http://dx.doi.org/10.1038/bmt.2016.288DOI Listing

Publication Analysis

Top Keywords

etoposide phosphate
4
phosphate hypersensitivity
4
hypersensitivity overcome
4
overcome desensitisation
4
desensitisation programme
4
programme enabling
4
enabling optimal
4
optimal therapy
4
therapy relapsed
4
relapsed hodgkin
4

Similar Publications

Introduction: A 16-month-old girl presented with bilateral germline retinoblastoma, with advanced retinoblastoma in the right eye and severe orbital retinoblastoma in the left eye. Patients typically receive treatment with the multimodal protocol consisting of chemotherapy, surgery, and radiotherapy, which has improved survival.

Case Presentation: Our patient elected for medical management with systemic chemotherapy instead of enucleation or exenteration.

View Article and Find Full Text PDF
Article Synopsis
  • Etoposide phosphate is a chemotherapy drug used for treating certain cancers, but it can cause hypersensitivity reactions, including severe cases like anaphylaxis, requiring different management strategies.
  • A 61-year-old woman with small-cell lung cancer experienced a severe allergic reaction during her treatment, resulting in cardiorespiratory arrest and requiring intensive medical intervention.
  • The case management involved a successful 16-step desensitization protocol without premedication, highlighting the need for customized treatment plans based on individual patient reactions and available medical resources.
View Article and Find Full Text PDF

Polyketides from the mangrove-derived fungus HNNU0006.

Nat Prod Res

July 2024

Key Laboratory of Tropical Medicinal Plant Chemistry of Hainan Province, Hainan Normal University, Haikou, Hainan, China.

Seven polyketides, including an undescribed depsidone () and six previously reported 3,6,8-trihydroxy-1-methylxanthone (), 7-hydroxy-2-(2-hydroxypropyl)-5-methylchromone (), methyl3-chloro-6-hydroxy-2-(4-hy-droxy-2-methoxy-6-methylphenoxy)-4- methoxybenzoate (), xylarianin A (), 4,5-dihydroxy-6-(6'-methylsalicyloxy)-2-hydro-xymethyl-2-cyclohexen-1-one () and alternariol (), have been isolated from cultures of the mangrove-derived fungus HNNU0006. The structure of compound was elucidated by extensive spectroscopic analysis and X-ray crystallography. Furthermore, all the compounds were evaluated their cytotoxic activities, and compounds and showed weak cytotoxicity against two cell lines Vero and A549 with IC values ranging from 95.

View Article and Find Full Text PDF

E-cigarette-/vape-associated lung injury (EVALI) refers to damage to lung tissue occurring as a result of e-cigarette utilization or via vaping of inhaled nicotine products. Vaping refers to the practice of inhaling an aerosol derived from heating a liquid or gas containing substances such as nicotine, cannabinoids, flavoring, or additives. Battery-operated e-cigarettes or vape pens are the vessels commonly used in this practice.

View Article and Find Full Text PDF

Background: Testicular cancer is the most common solid tumor affecting men aged 20-39 years old. About 95% of all testicular tumor is testicular germ cell tumor. Bilateral testicular tumor is a rare incident and has similar histopathology only in less than 5% of all testicular cancer patients.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!