Purpose: The goal of this contribution is to enhance the fidelity and switching speed of gradient and shim fields by advancing pre-emphasis toward broadband and full cross-term correction.
Theory And Methods: The proposed approach is based on viewing gradient and shim chains as linear, time-invariant (LTI) systems. Pre-emphasis is accomplished by inversion of a broadband digital system model. In the multiple-channel case, it amounts to a matrix of broadband filters that perform concerted self- and cross-term correction. This approach is demonstrated with gradients and shims up to the third order in a 7 Tesla whole-body MR system.
Results: Pre-emphasis by LTI model inversion is first verified by studying settling speeds and response behavior without and with the correction. It is then demonstrated for rapid shim updating, achieving substantially enhanced fidelity of field dynamics and shim settling within approximately 1 ms. In single-shot echo-planar imaging (EPI) acquisitions in vivo, this benefit is shown to translate into enhanced geometric fidelity.
Conclusions: The fidelity of gradient and shim dynamics can be greatly enhanced by pre-emphasis based on inverting a general LTI system model. Permitting shim settling on the millisecond scale, broadband multiple-channel pre-emphasis promises to render higher-order shimming fully versatile at the level of MRI sequence design. Magn Reson Med 78:1607-1622, 2017. © 2016 International Society for Magnetic Resonance in Medicine.
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http://dx.doi.org/10.1002/mrm.26531 | DOI Listing |
Diagnostics (Basel)
November 2024
Department of Medical Science, Soonchunhyang University, Asan 31538, Republic of Korea.
As the demand for early and accurate diagnosis of autism spectrum disorder (ASD) increases, the integration of machine learning (ML) and explainable artificial intelligence (XAI) is emerging as a critical advancement that promises to revolutionize intervention strategies by improving both accuracy and transparency. This paper presents a method that combines XAI techniques with a rigorous data-preprocessing pipeline to improve the accuracy and interpretability of ML-based diagnostic tools. Our preprocessing pipeline included outlier removal, missing data handling, and selecting pertinent features based on clinical expert advice.
View Article and Find Full Text PDFInt J Mol Sci
October 2024
Graduate School of Green-Bio Science and Crop Biotech Institute, Kyung Hee University, Yongin 17104, Republic of Korea.
Efficient sucrose transport and metabolism are vital for seed and pollen development in plants. Cell wall invertases (CINs) hydrolyze sucrose into glucose and fructose, maintaining a sucrose gradient in the apoplast of sink tissues. In rice, two CIN isoforms, OsCIN1 and OsCIN2, were identified as being specifically expressed in the anthers but not in pollen.
View Article and Find Full Text PDFEur Heart J Cardiovasc Imaging
December 2024
Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Aims: Patients with moderate aortic stenosis (AS) show a poor prognosis if they have high-risk features. We investigated herein the incremental prognostic value of left ventricular (LV) and left atrial (LA) strain in patients with moderate AS.
Methods And Results: In a cohort of 923 patients with moderate AS (median age 74 years, men 55%, aortic valve area 1.
Nat Commun
November 2024
Department of Mechanical and Aerospace Engineering, Princeton University, Princeton, NJ, USA.
Microtubules are dynamic filaments that assemble spindles for eukaryotic cell division. As the concentration profiles of soluble tubulin and regulatory proteins are non-uniform during spindle assembly, we asked if diffusiophoresis - motion of particles under solute gradients - can act as a motorless transport mechanism for microtubules. We identify the migration of stable microtubules along cytoplasmic and higher concentration gradients of soluble tubulin, MgCl, Mg-ATP, Mg-GTP, and RanGTP at speeds O(100) nm/s, validating the diffusiophoresis hypothesis.
View Article and Find Full Text PDFMagn Reson Med
March 2025
UT Southwestern Medical Center, Dallas, Texas, USA.
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