The migratory phenomenon in Portugal has become one of the main factors for the genetic variability. In the last few years, a new class of autosomal insertion/deletion markers-InDel-has attracted interest in forensic genetics. Since there is no data for InDel markers of Portuguese-speaking African countries (PALOP) immigrants living in Lisboa, our aim is the characterization of those groups of individuals by typing them with at least 30 InDel markers and to compare different groups of individuals/populations. We studied 454 bloodstain samples belonging to immigrant individuals from Angola, Guinea-Bissau, and Mozambique. DNA extraction was performed with the Chelex® 100 method. After extraction, all samples were typed with the Investigator® DIPplex method. Through the obtained results, allelic frequencies show that all markers are at Hardy-Weinberg equilibrium, and we can confirm that those populations show significant genetic distances between themselves, between them, and the host Lisboa population. Because of this, they introduce genetic variability in Lisboa population.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s00414-016-1484-3 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Variants of the ABCG2 gene in Mexican mestizo patients with prostate cancer.
Cell Mol Biol (Noisy-le-grand)
January 2025
Departamento de Biología Molecular y Genómica y Departamento de Disciplinas Filosófico Metodológicas e Instrumentales. Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Jalisco, México.
ABCG2 transporter protein is one of several markers of prostate cancer stem cells (PCSCs). Gene variants of ABCG2 could affect protein expression, function, or both. The aim of this study was to identify the genetic variability of the ABCG2 gene in Mexican patients with prostate cancer.
View Article and Find Full Text PDFCausal effects of retinol and vitamin D on tongue cancer risk: a mendelian randomization study.
BMC Oral Health
January 2025
Department of Stomatology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
Background: Previous studies have indicated that retinol and vitamin D may be associated with the oncogenesis of tongue cancer. Therefore, we aimed to assess the causal relationships of retinol and vitamin D with the risk of tongue cancer using the two-sample Mendelian randomization (MR) method.
Methods: Single nucleotide polymorphisms (SNPs) related to retinol, vitamin D and tongue cancer were obtained from the up-to-date genome-wide association study (GWAS) catalogue, which was screened for instrumental variables (IVs).
Differences in gut microbial diversity and composition between growth phenotypes of farmed juvenile sandfish, Holothuria scabra.
BMC Microbiol
January 2025
The Marine Science Institute, College of Science, University of the Philippines Diliman, Quezon City, Philippines.
Background: The observed growth variability of different aquaculture species in captivity hinders its large-scale production. For the sandfish Holothuria scabra, a tropical sea cucumber species, there is a scarcity of information on its intestinal microbiota in relation to host growth, which could provide insights into the processes that affect growth and identify microorganisms with probiotic or biochemical potential that could improve current production strategies. To address this gap, this study used 16 S rRNA amplicon sequencing to characterize differences in gut and fecal microbiota among large and small juveniles reared in floating ocean nurseries.
View Article and Find Full Text PDFDevelopment of a mitochondrial mini-barcode and its application in metabarcoding for identification of leech in traditional Chinese medicine.
Sci Rep
January 2025
National Key Laboratory of Lead Druggability Research, Shanghai Institute of Pharmaceutical Industry, State Institute of Pharmaceutical Industry, 201203, Shanghai, People's Republic of China.
In Traditional Chinese Medicine (TCM), the medicinal leech is vital for treatments to promote blood circulation and eliminate blood stasis. However, the prevalence of counterfeit leech products in the market undermines the quality and efficacy of these remedies. Traditional DNA barcoding techniques, such as the COI barcode, have been limited in their application due to amplification challenges.
View Article and Find Full Text PDFImproved dynamic programming method for solving multi-objective and multi-stage decision-making problems.
Sci Rep
January 2025
School of Electromechanical Engineering, Guangdong University of Technology, Guangzhou, 510006, China.
Multi-objective and multi-stage decision-making problems require balancing multiple objectives at each stage and making optimal decision in multi-dimensional control variables, where the commonly used intelligent optimization algorithms suffer from low solving efficiency. To this end, this paper proposes an efficient algorithm named non-dominated sorting dynamic programming (NSDP), which incorporates non-dominated sorting into the traditional dynamic programming method. To improve the solving efficiency and solution diversity, two fast non-dominated sorting methods and a dynamic-crowding-distance based elitism strategy are integrated into the NSDP algorithm.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!