AI Article Synopsis
- Millions of cases of hand, foot, and mouth disease (HFMD) have been reported in China since 2008, prompting a study on its epidemiology in Fujian province.
- The research revealed shared characteristics of HFMD across southern China, including seasonal patterns and demographic trends, while also linking the severity of illness to specific virus serotypes.
- At least 22 different enterovirus serotypes were identified, with some clades associated with enterovirus 71 and coxsackievirus A16, highlighting the complexity of the epidemic.
Article Abstract
Millions of cases of hand, foot, and mouth disease (HFMD) have been reported annually in mainland China since 2008. In this study, we investigated the epidemiology and etiology of an HFMD epidemic in Fujian province, which is located in subtropical southeastern China. Our study found similar epidemiological features of HFMD in southern areas of China, including seasonality and demographic distribution, as well as correlation between severity of illness and serotype. At least 22 serotypes of other enterovirus co-circulating with enterovirus 71 were found to belong to clade C4a, and those circulating with coxsackievirus A16 were associated with clades B1a and B1b.
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| http://dx.doi.org/10.1007/s00705-016-3127-x | DOI Listing |
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