Background: In the altiplano of Northern Chile the plant is habitually used as an infusion to relieve the effects of altitude sickness (locally known as "puna"). It is also used to alleviate the bronchitis, whooping cough, asthma, stomachache, tiredness and fever. The extreme conditions under which these plant grow and scientific data that shows the inhibiting potential of the essential oils of plants of the genus represents great potential in the study of their application to control pathogens like .
Methods: The essential oil from aerial parts of was isolated by hydrodistillation and the chemical composition characterized by GC-MS analyses. The antibacterial potential and determination of MIC value, was estimated in both micro and macro dilution method.
Results: The GC-MS analysis of essential oil of showed the presence of methyl cinnamate (44.9 %), -cymenol (27.2 %), and terpinen-4-ol (6.8 %), α-terpineol (4.1 %), -cadinol (3.5 %), methyl hydrocinnamate (2.1 %), δ-cadinene (2.0 %), -cymene (1.9 %), γ-terpinene (1.8 %), α-cadinol (1.6 %), -sabinene hydrate (1.1 %), caryophyllene (0.9 %), β-pinene (0.8 %), and α-terpinene (0.6 %) as major components. Moreover, the oil of exhibited an important antibacterial activity with a diameter of inhibition zone growth of 22 mm and the MIC value of 0.4 mg/mL against pathogenic bacteria .
Conclusions: The results show for the first time the antibacterial activity of the essential oils of against the pathogen, an activity that can be applied as a preventive treatment against the action of pathogen.
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| http://dx.doi.org/10.1186/s40064-016-3469-6 | DOI Listing |
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