Design and Validation of a Vacuum Assisted Anchorage for the Uniaxial Tensile Testing of Soft Materials.

Soft Mater

Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA; Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, PA; Department of Surgery, University of Pittsburgh, Pittsburgh, PA; Center for Vascular Remodeling and Regeneration, University of Pittsburgh, Pittsburgh, PA; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA.

Published: January 2016

AI Article Synopsis

  • Current testing methods for soft materials often use compression grips, which can damage delicate materials.
  • We developed a vacuum-assisted anchor (VAA) to securely hold soft tissues during tensile testing without causing harm.
  • Using the VAA, we successfully tested fibrin gels, revealing significant differences in mechanical properties based on varying fibrinogen concentrations.

Article Abstract

Current commercial tensile testing systems use spring-loaded or other compression-based grips to clamp materials in place posing a problem for very soft or delicate materials that cannot withstand this mechanical clamping force. In order to perform uniaxial tensile tests on soft tissues or materials, we have created a novel vacuum-assisted anchor (VAA). Fibrin gels were subjected to uniaxial extension, and the testing data was used to determine material mechanical properties. Utilizing the VAA, we achieved successful tensile breaks of soft fibrin gels while finding statistically significant differences between the mechanical properties of gels fabricated at two different fibrinogen concentrations.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082747PMC
http://dx.doi.org/10.1080/1539445X.2016.1141787DOI Listing

Publication Analysis

Top Keywords

uniaxial tensile
8
tensile testing
8
fibrin gels
8
mechanical properties
8
design validation
4
validation vacuum
4
vacuum assisted
4
assisted anchorage
4
anchorage uniaxial
4
tensile
4

Similar Publications

Nosé-Hoover Integrators at-a-Glance: Barostat Integration Has a Demonstrable Effect on Uniaxial Tension Results of Solid Materials.

J Chem Theory Comput

January 2025

Mechanical and Industrial Engineering Department, Northeastern University, Boston, Massachusetts 02115, United States.

Article Synopsis
  • Molecular dynamics is crucial for studying tensile stress in nanomaterials, but many studies lack detailed information on thermostat and barostat damping parameters.
  • The paper demonstrates how the integration of barostat affects system dynamics during uniaxial tests using the Nosé-Hoover scheme by examining three different material systems: 2D graphene, 3D continuous aluminum, and 3D discontinuous polyvinyl alcohol.
  • High barostat damping parameters in isobaric-isothermal (NPT) simulations show a close correlation with isochoric-isothermal (NVT) methods, indicating that small changes in damping parameters can significantly impact stress responses, particularly increasing triaxial strain levels.
View Article and Find Full Text PDF

Influence of rock heterogeneity on the correlation between uniaxial compressive strength and Brazilian tensile strength.

Sci Rep

January 2025

Key Laboratory of Geological Safety of Coastal Urban Underground Space, MNR, Qingdao, 266101, China.

To offer guidance for using Brazilian tensile strength (BTS) to estimate UCS of heterogeneous rocks, this study uses sandstone (fine or coarse grain) and gneiss (0°, 45°, 90° inclined anisotropy) to investigate the influence of grain size or anisotropy on the correlations of UCS-BTS. According to the regression analysis, there is no significant equation of UCS-BTS for rocks with vertical anisotropy. The grain size variation or multidirectional anisotropy can result in a decrease in the determination coefficient value of correlations.

View Article and Find Full Text PDF

Study on uniaxial compression mechanical properties of 3D printed columnar joint test blocks.

Sci Rep

December 2024

College of Civil Engineering and Transportation, Hohai University, Nanjing, 210098, China.

The columnar joint skeleton of 3D printed Acrylonitrile Butadiene Styrene (ABS) material, the skeleton of cement mortar and ultraviolet aging treatment are combined to pour the columnar joint rock mass (CJRM) test block. The strength, deformation, energy and failure modes of the specimens with different dip angles were analyzed by uniaxial compression test. The influence of joint skeleton on the strength of the test block was analyzed.

View Article and Find Full Text PDF

The development of artificial skin that accurately mimics the mechanical properties of human skin is crucial for a wide range of applications, including surgical training for burn injuries, biomechanical testing, and research in sports injuries and ballistics. While traditional materials like gelatin, polydimethylsiloxane (PDMS), and animal skins (such as porcine and bovine skins) have been used for these purposes, they have inherent limitations in replicating the intricate properties of human skin. In this work, we conducted uniaxial tensile tests on freshly obtained cadaveric skin to analyze its mechanical properties under various loading conditions.

View Article and Find Full Text PDF

Mechanical function of the annulus fibrosus is preserved following quasi-static compression resulting in endplate fracture.

Clin Biomech (Bristol)

December 2024

Department of Kinesiology and Physical Education, Wilfrid Laurier University, Waterloo, Ontario, Canada; Department of Health Sciences, Wilfrid Laurier University, Waterloo, Ontario, Canada. Electronic address:

Background: Vertebral fractures in young populations are associated with intervertebral disc disorders later in life. However, damage to the annulus fibrosus has been observed in rapidly loaded spines even without the subsequent occurrence of a fracture. Therefore, it may not be the fracture event that compromises the disc, but rather the manner in which the disc is loaded.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!