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Predictive Role of HE4 in Diagnosis of Ovarian Tumors.
J Obstet Gynaecol India
October 2024
Obstretrics and Gynecology, IGIMS, Patna, India.
Background: Approximately 20% of women develop an ovarian cyst or pelvic mass at some point in their lives. Due to high false positivity of CA-125, women with various benign ovarian tumors simulating malignant masses undergo extensive debulking surgery resulting in increased morbidity. Serum HE4 is a useful test for better discrimination of benign or malignant nature of pelvic masses in preoperative period.
View Article and Find Full Text PDFAccuracy of ultrasound, magnetic resonance imaging and intraoperative frozen section in the diagnosis of ovarian tumours: data from a London tertiary centre.
BJC Rep
July 2024
Department of Gynaecological Oncology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Article Synopsis
- Ovarian cancer has the worst prognosis among gynecological cancers, making accurate pre-operative and intraoperative diagnosis crucial for improving patient outcomes.* -
- A study reviewed 156 cases of ovarian masses, comparing final histological diagnoses with ultrasound, MRI, and frozen section (FS) to determine diagnostic accuracy; FS showed high sensitivity for detecting malignancies.* -
- While FS is effective for diagnosing ovarian tumors, the study highlights ongoing challenges in accurately diagnosing borderline ovarian tumors using both imaging techniques and FS.*
Incidental findings of borderline ovarian tumor or ovarian cancer - real-world data on surgical and oncological outcomes.
Front Oncol
October 2024
Department of Obstetrics and Gynecology, Bern University Hospital and University of Bern, Bern, Switzerland.
Introduction: Centralization of ovarian cancer treatment is associated with higher rates of optimal surgery and longer survival. However, preoperative diagnosis of ovarian cancer is challenging and some diagnoses are made incidentally after surgery. This study investigated the surgical and oncological outcomes of patients with incidental findings of borderline ovarian tumors or ovarian cancer who were centralized postoperatively and treated with a two-stage surgical procedure, and compared these with those of patients with adnexal masses of suspected malignancy who were offered a single-stage surgical procedure with intraoperative frozen section in a tertiary hospital.
View Article and Find Full Text PDFCholangiocarcinoma.
Surg Clin North Am
December 2024
Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Shanford Univeristy Hospital, 300 Pasteur Drive, H3680, Stanford, CA 94305-5655, USA. Electronic address:
Management of intrahepatic cholangiocarcinoma relies on a thorough understanding of the tumor's location and proximity to critical vasculobiliary structures. Mid-common bile duct tumors may require hemihepatectomy or pancreatoduodenectomy based on the status of the intraoperative frozen section. Distal common bile tumors are treated with pancreatoduodenectomy.
View Article and Find Full Text PDFBorderline tumours of the ovary: A 37-year experience at a tertiary referral centre.
Aust N Z J Obstet Gynaecol
October 2024
Department of Oncology and Dysplasia, Royal Women's Hospital, Melbourne, Victoria, Australia.
Introduction: Borderline ovarian tumours (BOT) are a common epithelial ovarian tumours. Typically diagnosed at an early stage with a good prognosis, many BOT are treated conservatively. Recurrence is common.
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