A synthetic method for the efficient assembly of bicyclo[2.2.1]hept-2-en-7-ones that relies on gold(I)-catalyzed Rautenstrauch rearrangement followed by Brønsted acid-mediated formal [3 + 2]-cycloaddition/deacetylation of 1,8-diynyl vinyl acetates at room temperature under atmospheric conditions is described.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.orglett.6b03049 | DOI Listing |
Publication Analysis
Top Keywords
18-diynyl vinyl
8
vinyl acetates
8
gold- brønsted
4
brønsted acid-catalyzed
4
acid-catalyzed cycloisomerization
4
cycloisomerization 18-diynyl
4
acetates bicyclo[221]hept-2-en-7-ones
4
bicyclo[221]hept-2-en-7-ones synthetic
4
synthetic method
4
method efficient
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!