The synthesis of enantioenriched small molecules is an ongoing goal of organic chemists. This focus review explores the use of kinetic resolutions catalyzed by chiral Brønsted acids. Methods include classic kinetic resolutions and dynamic kinetic resolutions. The small molecules obtained are potentially valuable intermediates in the synthesis of biologically important compounds.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077028 | PMC |
http://dx.doi.org/10.1002/ajoc.201600021 | DOI Listing |
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