AI Article Synopsis
- - This study analyzes chemical exposure levels among pregnant women in France who gave birth in 2011, focusing on various environmental pollutants as part of the French Human Biomonitoring program.
- - Biological samples were collected from 4145 women, and the study provided representative data on biomarker levels for many chemicals, including Bisphenol A and various pesticides.
- - Results indicate that while some pollutants like lead and mercury are decreasing, others, such as pyrethroids, remain concerning and highlight the need for ongoing monitoring of environmental exposure during pregnancy.
Article Abstract
Background: As part of the perinatal component of the French Human Biomonitoring (HBM) program, biomarkers levels of various chemicals have been described among pregnant women having given birth in continental France in 2011 and who have been enrolled in the Elfe cohort (French Longitudinal Study since Childhood). This paper describes the design of the study and provides main descriptive results regarding exposure biomarkers levels.
Methods: Exposure biomarkers were measured in biological samples collected at delivery from pregnant women randomly selected among the participants in the clinical and biological component of the Elfe cohort (n=4145). The geometric mean and percentiles of the levels distribution were estimated for each biomarker. The sampling design was taken into account in order to obtain estimates representative of the French pregnant women in 2011.
Results: Results provide a nation-wide representative description of biomarker levels for important environmental contaminants among pregnant women who gave birth in France in 2011. Bisphenol A (BPA), and some metabolites of phthalates, pesticides (mainly pyrethroids), dioxins, furans, polychlorobiphenyls (PCBs), brominated flame retardants (BFRs), perfluorinated compounds (PFCs) and metals (except uranium) were quantified in almost 100% of the pregnant women. Some compounds showed a downward trend compared to previous studies (lead, mercury), but others did not (pyrethroids) and should be further monitored.
Conclusion And Perspectives: The present results show that French pregnant women are exposed to a wide variety of pollutants, including some that have been banned or restricted in France.
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| http://dx.doi.org/10.1016/j.envint.2016.10.013 | DOI Listing |
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