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Bundled-Optode Method in Functional Near-Infrared Spectroscopy. | LitMetric

Bundled-Optode Method in Functional Near-Infrared Spectroscopy.

PLoS One

Department of Rehabilitation Medicine, School of Medicine, Pusan National University & Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, 20, Geumo-ro, Mulgeum-eup, Yangsan-si, Gyeongsangnam-do, 50612, Republic of Korea.

Published: June 2017

AI Article Synopsis

Article Abstract

In this paper, a theory for detection of the absolute concentrations of oxy-hemoglobin (HbO) and deoxy-hemoglobin (HbR) from hemodynamic responses using a bundled-optode configuration in functional near-infrared spectroscopy (fNIRS) is proposed. The proposed method is then applied to the identification of two fingers (i.e., little and thumb) during their flexion and extension. This experiment involves a continuous-wave-type dual-wavelength (760 and 830 nm) fNIRS and five healthy male subjects. The active brain locations of two finger movements are identified based on the analysis of the t- and p-values of the averaged HbOs, which are quite distinctive. Our experimental results, furthermore, revealed that the hemodynamic responses of two-finger movements are different: The mean, peak, and time-to-peak of little finger movements are higher than those of thumb movements. It is noteworthy that the developed method can be extended to 3-dimensional fNIRS imaging.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082888PMC
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0165146PLOS

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