The X-ray deformable mirror (XDM) is becoming widely used in the present synchrotron/free-electron laser facilities because of its flexibility in correcting wavefront errors or modification of the beam size at the sample location. Owing to coupling among the N actuators of an XDM, (N + 1) or (2N + 1) scans are required to learn the response of each actuator one by one. When the mirror has an important number of actuators (N) and the actuator response time including stabilization or the necessary metrology time is long, the learning process can be time consuming. In this work, a fast and accurate method is presented to drive an XDM to a target shape usually with only three or four measurements during inspection. The metrology data are used as feedback to calculate the curvature discrepancy between the current and the target shapes. Three different derivative estimation methods are introduced to calculate the curvature from measured data. The mirror shape is becoming close to the target through iterative compensations. The feasibility of this simple and effective approach is demonstrated by a series of experiments.
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http://dx.doi.org/10.1107/S1600577516014600 | DOI Listing |
Chaos
January 2025
College of Science, Civil Aviation University of China, Tianjin 300300, China.
Adolescent idiopathic scoliosis (AIS), which typically occurs in patients between the ages of 10 and 18, can be caused by a variety of reasons, and no definitive cause has been found. Early diagnosis of AIS or timely recognition of progression is crucial for the prevention of spinal deformity and the reduction of the risk of surgery or postponement. However, it remains a significant challenge.
View Article and Find Full Text PDFEur J Neurol
January 2025
Epilepsy Center, Department of Neurology, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy.
Background: Epileptiform activity, including status epilepticus (SE), occurs in up to one-third of comatose survivors of cardiac arrest and may predict poor outcome. The relationship between SE and hypoxic-ischemic brain injury (HIBI) is not established.
Methods: This is a single-center retrospective study on consecutive patients with post-anoxic super-refractory SE.
Elife
January 2025
Center for Medical Genetics Ghent, Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.
Heritable fragile bone disorders (FBDs), ranging from multifactorial to rare monogenic conditions, are characterized by an elevated fracture risk. Validating causative genes and understanding their mechanisms remain challenging. We assessed a semi-high throughput zebrafish screening platform for rapid in vivo functional testing of candidate FBD genes.
View Article and Find Full Text PDFJ Spine Surg
December 2024
Department of Neurosurgery, The Gemelli University Hospital, Rome, Italy.
Background: Aneurysmal bone cysts (ABCs) are benign, blood-filled neoplasms causing bone destruction, often requiring resection. However, challenges arise, especially at the cranio-cervical junction, where proximity to critical structures limits removal. Non-surgical options include selective arterial embolization (SAE) as main treatment, while Denosumab and centrifugated bone marrow emerge as experimental alternatives.
View Article and Find Full Text PDFBiomed Opt Express
January 2025
Department of Bioengineering, University of Washington, Seattle, WA 98105, USA.
The motion of the trabecular meshwork (TM) facilitates the aqueous drainage from the anterior chamber to the venous system, thereby maintaining normal intraocular pressure. As such, characterizing the TM motion is valuable for assessing the functionality of the aqueous outflow system, as demonstrated by previous phase-sensitive optical coherence tomography (OCT) studies. Current methods typically acquire motion from a single cross-sectional plane along the circumference of the anterior chamber.
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