AI Article Synopsis
- Enzymes act as efficient catalysts that can interact with a variety of complex molecules, facilitating reactions with high selectivity.
- Biocatalysis simplifies chemical transformations by eliminating the need for complicated protection and deprotection steps found in traditional organic synthesis.
- The review focuses on the use of lipases in various synthetic applications, including the resolution of important pharmaceuticals and the development of advanced materials like drug carriers and solar cells.
Article Abstract
Enzymes, being remarkable catalysts, are capable of accepting a wide range of complex molecules as substrates and catalyze a variety of reactions with a high degree of chemo-, stereo- and regioselectivity in most of the reactions. Biocatalysis can be used in both simple and complex chemical transformations without the need for tedious protection and deprotection chemistry that is very common in traditional organic synthesis. This current review highlights the applicability of one class of biocatalysts viz."lipases" in synthetic transformations, the resolution of pharmaceutically important small molecules including polyphenols, amides, nucleosides and their precursors, the development of macromolecular systems (and their applications as drug/gene carriers), flame retardants, polymeric antioxidants and nanocrystalline solar cells, etc.
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| http://dx.doi.org/10.1039/c6cs00147e | DOI Listing |
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