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| http://dx.doi.org/10.21037/tau.2016.07.04 | DOI Listing |
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Dengue is a viral disease present in many regions of the world. Aedes aegypti transmits it, and the most effective way to eliminate the mosquito is during the larval stage. Seaweeds possess metabolites with insecticidal properties, making them potential sources of new larvicides and viable alternatives to synthetic products used to control insect vectors of diseases.
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Chemosensors to detect ions have been increasingly studied to distinguish hazardous and economic species, and detecting and recuperating ions is crucial. Searching for a low-cost technique and better chemosensors, our group presents exciting results, using the UV-Vis technique to evidence the effective interaction between the ligand (1) and the anions F, Ac, and CrO, as well as the NMR titration. Low LOD for these ions (3.
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The presence of IKZF1 deletions has been associated with an increased relapse rate in B-cell precursor acute lymphoblastic leukaemia (BCP-ALL). There is a particular subset of IKZF1 cases called IKZF1 (defined by the co-occurrence of IKZF1 and deletions in CDKN2A/B, PAX5, or the PAR1 region, in the absence of ERG deletions), which is also associated with worse prognosis, but some recent studies have not found major differences between the IKZF1 and IKZF1 groups. Therefore, the IKZF1 group still needs further comprehension and our study aims to characterise the molecular heterogeneity and identify molecular markers exclusively associated with IKZF1.
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