Introduction: Animal pericardial patches are widely used in adult and pediatric cardiac surgery. A search is ongoing for a new material with optimal surgical properties that will reduce intraoperative bleeding and the occurrence of restenosis, calcification, and pseudoaneurysms in long-term observation. One product of interest is the CardioCel bovine pericardial patch.
Aim: Evaluation of the short-term results of CardioCel bovine pericardial patch implantation during pediatric cardiac surgery.
Material And Methods: The study included 8 patients who underwent surgical correction of congenital cardiac defects between January 2015 and February 2016. Pericardial patches were used to repair supravalvular aortic stenosis and reconstruct the aortic arch and pulmonary arteries. The age of the patients ranged from 10 days to 14 years.
Results: There were no hospital deaths. The new material exhibited satisfactory durability and elasticity during surgery, facilitating optimal adaptation of the patch to the patient's tissues. No significant bleeding was reported from the suture site. The median duration of follow-up was 58 days. During the follow-up, there were no symptoms of pseudoaneurysm formation, patch thickening, or calcification in the areas where the pericardial patches were implanted. No clinical or laboratory symptoms of infection were observed in locations where the new material was applied.
Conclusions: Satisfactory surgical properties of the patch were observed intraoperatively. Positive results using the new pericardial patch were obtained in short-term follow-up.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071587 | PMC |
http://dx.doi.org/10.5114/kitp.2016.62607 | DOI Listing |
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu
March 2024
Division of Cardiac Surgery, Children's National Hospital, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia.. Electronic address:
The so-called Commando procedure, initially described by David and colleagues, consists in the reconstruction of the mitro-aortic fibrous lamina by a patch that enlarges both annuli. Its use has been described to upsize the aortic and mitral annulus for double valve replacement in adolescents. We describe a modified technique of this reconstruction of the fibrous skeleton of the heart, combined with Konno procedure to further enlarge the aortic annulus.
View Article and Find Full Text PDFEur J Cardiothorac Surg
November 2023
Department of Cardiac Surgery, Boston Children's Hospital, Boston, MA, USA.
Objectives: Thick-patch pulmonary homograft, autologous pericardium and CardioCel Neo are common patch materials for aortic arch reconstruction. Insufficient data exist on sutured patch strength and limits of use. We evaluated failure strength of these materials to develop a failure prediction model for clinical guidance.
View Article and Find Full Text PDFEur J Cardiothorac Surg
October 2023
Queensland Paediatric Cardiac Service (QPCS), Queensland Children's Hospital, Brisbane, Australia.
Objectives: To assess the mid-term performance of CardioCel for the repair of congenital heart defects.
Methods: Data were retrospectively collected from databases and hospital records in 3 congenital cardiac surgery centres in Australia. Kaplan-Meier curves and log-rank tests were used to test for associations between patient age, gender, patch type and site of implantation.
World J Pediatr Congenit Heart Surg
March 2023
Queensland Paediatric Cardiac Service (QPCS), Queensland Children's Hospital, Brisbane, Australia.
A systematic review was performed for evaluation of the performance of CardioCel in cardiac surgery. The review included all studies published from January 2013 to December 2020. We conclude that CardioCel is a strong, flexible tissue substitute with good handling characteristics and a low incidence of thrombosis, aneurysm formation, infection, or structural degeneration.
View Article and Find Full Text PDFWorld J Pediatr Congenit Heart Surg
March 2022
Queensland Paediatric Cardiac Service, 67568Queensland Children's Hospital, Brisbane, Australia.
CardioCel is bovine pericardium which is subjected to a novel tissue engineering process (ADAPT) to reduce cytotoxicity and retard calcification while maintaining strength and elasticity. We present a case where CardioCel showed rapid degeneration and calcification after repair of an aortic valve.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!