AI Article Synopsis
- Atypical thymic carcinoid is a very rare neuroendocrine tumor originating from the thymus, and the paper aims to enhance understanding of its clinical characteristics and improve diagnosis and treatment options.
- Three cases of atypical thymic carcinoid are analyzed, highlighting nonspecific initial symptoms, detection of an anterior mediastinal mass on CT scans, and the surgical approach taken, which included total thymectomy and postoperative therapies.
- The study also compiles relevant literature to provide a comprehensive reference for diagnosing and treating atypical thymic carcinoid effectively.
Article Abstract
Atypical thymic carcinoid is an extremely rare thymic neuroendocrine tumor derived from the neuroendocrine system. The aims of this paper were to investigate the clinical features of atypical thymic carcinoid and collate information and experience to improve the diagnosis and treatment of this disease. We describe three cases of atypical carcinoid of the thymus; clinical features, pathological data, treatment modalities, and short-term patient outcomes were summarized and analyzed. The initial clinical symptoms and signs of all three patients were nonspecific and an anterior mediastinal mass was found in each patient on chest computed tomography scan. All three patients underwent surgical resection (total thymectomy and complete excision of the tumor), followed by postoperative radiotherapy, with or without chemotherapy. The diagnoses of three patients were confirmed by pathological and immunohistochemical evaluation. We also present a review of the literature to collate as much information as possible and provide a reference for proper diagnosis and treatment of atypical thyroid carcinoid.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066990 | PMC |
| http://dx.doi.org/10.2147/OTT.S109693 | DOI Listing |
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