The mechanism of diffusion of helical particles in the new screw-like nematic phase is studied by molecular dynamics numerical simulation. Several dynamical indicators are reported that evidence and microscopically characterise the special translo-rotational motion by which helical particles move in this chiral liquid-crystalline phase. Besides mean square displacements and diffusion coefficients resolved parallel and perpendicular to the nematic director, a suitable translo-rotational van Hove self-correlation function and a sequence of translational and rotational velocity, self- and distinct-, time correlation functions are calculated. The analysis of all these correlation functions elicits the operativeness of the aforementioned coupled mechanism and allows its short- and long-time quantitative characterisation.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1063/1.4963016 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Time-varying 3D optical torque via a single beam.
Nat Commun
January 2025
Department of Optics and Optical Engineering, University of Science and Technology of China, Hefei, China.
The spin angular momentum (SAM) plays a significant role in light-matter interactions. It is well known that light carrying SAM can exert optical torques on micro-objects and drive rotations, but 3D rotation around an arbitrary axis remains challenging. Here, we demonstrate full control of the 3D optical torque acting on a trapped microparticle by tailoring the vectorial SAM transfer.
View Article and Find Full Text PDFThe proline-rich antimicrobial peptide Api137 disrupts large ribosomal subunit assembly and induces misfolding.
Nat Commun
January 2025
Institute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, Universität Leipzig, Leipzig, Germany.
The proline-rich antimicrobial designer peptide Api137 inhibits protein expression in bacteria by binding simultaneously to the ribosomal polypeptide exit tunnel and the release factor (RF), depleting the cellular RF pool and leading to ribosomal arrest at stop codons. This study investigates the additional effect of Api137 on the assembly of ribosomes using an Escherichia coli reporter strain expressing one ribosomal protein per 30S and 50S subunit tagged with mCherry and EGFP, respectively. Separation of cellular extracts derived from cells exposed to Api137 in a sucrose gradient reveals elevated levels of partially assembled and not fully matured precursors of the 50S subunit (pre-50S).
View Article and Find Full Text PDFBottom-up design of calcium channels from defined selectivity filter geometry.
bioRxiv
December 2024
Department of Biochemistry, University of Washington, Seattle, WA, USA.
Native ion channels play key roles in biological systems, and engineered versions are widely used as chemogenetic tools and in sensing devices. Protein design has been harnessed to generate pore-containing transmembrane proteins, but the capability to design ion selectivity based on the interactions between ions and selectivity filter residues, a crucial feature of native ion channels, has been constrained by the lack of methods to place the metal-coordinating residues with atomic-level precision. Here we describe a bottom-up RFdiffusion-based approach to construct Ca channels from defined selectivity filter residue geometries, and use this approach to design symmetric oligomeric channels with Ca selectivity filters having different coordination numbers and different geometries at the entrance of a wide pore buttressed by multiple transmembrane helices.
View Article and Find Full Text PDFEnhanced stability and oxidation resistance of Bunge seed oil Pickering emulsion using rice bran protein modified by phytic acid.
Food Chem X
January 2025
School of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, China.
The potential applications of Bunge seed oil in the food and medical industries are constrained by its susceptible fatty acid composition, which is prone to oxidation. In this study, rice bran protein (RBP) was employed as an emulsifier for the fabrication of Bunge seed oil Pickering emulsion. The impact of antioxidant-phytic acid (PA) on the stability of Pickering emulsion and the underlying mechanisms were further investigated.
View Article and Find Full Text PDFThe Basic Architecture of Viruses.
Subcell Biochem
December 2024
Department of Macromolecular Structure, Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain.
Viruses are elegant macromolecular assemblies and constitute a paradigm of the economy of genomic resources; they must use simple general principles to complete their life cycles successfully. Viruses need only one or a few different capsid structural subunits to build an infectious particle, which is possible for two reasons: extensive use of symmetry and built-in conformational flexibility. Although viruses come in many shapes and sizes, two major symmetric assemblies are found: icosahedral and helical.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!