The treatment of soft tissue sarcomas is at present a multidisciplinary process. In Switzerland, patients are too often referred to specialized centers after an inadequate management. The general principles of biopsy, surgery, radiotherapy and chemotherapy are reviewed in the light of the biological behaviour of these tumors. Emphasis is made on the role of adjuvant chemotherapy that is not yet established and that is the subject of an ongoing Swiss Study. A collaboration to the study of the Swiss centers and the surgeons is needed in order to improve the quality of treatment of these tumors.

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