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Effect of timing of antibiotic use on premature rupture of membranes and its impact on reproductive tract infection and fetal membrane cell scorching indicators.
Afr J Reprod Health
December 2024
Department of Obstetrics and Gynecology, Changshu Hospital Affiliated to Nanjing University of Chinese Medicine,Changshu 215500, Jiang Su,China.
The study was designed to appraise the effects of early antibiotic administration on reproductive tract infections and fetal membrane cell scorching in instances of premature rupture of membranes (PROM). A total of 107 pregnant women diagnosed with PROM between July 2020 and June 2022 were randomly assigned to two groups: the Intervention (n=54), where ampicillin were administered within 24 hours of PROM onset, and the control group (n=53), where ampicillin were given 24-48 hours after PROM. Maternal and neonatal outcomes, incidence of reproductive tract infections, and fetal membrane cell scorching indicators (Caspase-1, Caspase -3, Caspase-9 and IL-β) were compared.
View Article and Find Full Text PDFSeparating Infectious Proctitis from Inflammatory Bowel Disease-A Common Clinical Conundrum.
Microorganisms
November 2024
Department of Gastroenterology, St George's University Hospital, London SW17 0QT, UK.
Proctitis refers to inflammation in the rectum and may result in rectal bleeding, discharge, urgency, tenesmus, and lower abdominal pain. It is a common presentation, particularly in genitourinary medicine and gastroenterology, as the two most common causes are sexually transmitted infections and inflammatory bowel disease. The incidence of infective proctitis is rising, particularly amongst high-risk groups, including men who have sex with men, those with HIV seropositive status, and those participating in high-risk sexual behaviours.
View Article and Find Full Text PDFAssociation Between and with Inflammation in Polycystic Ovary Syndrome: A Cross-Sectional Study.
Medicina (Kaunas)
December 2024
Department of Obstetrics and Gynecology, Balıkesir University School of Medicine, 10145 Balıkesir, Turkey.
: Chronic low-grade inflammation occurs in polycystic ovary syndrome (PCOS), and there are many contributing factors. In this study, we aimed to investigate and infections in patients with PCOS and to evaluate the association between these microorganisms and the inflammatory process in the etiology of the disease. : This comparative cross-sectional clinical study was conducted at Balıkesir University Hospital and included 40 female patients diagnosed with PCOS in the gynecology outpatients clinic and 40 healthy female controls.
View Article and Find Full Text PDFFrom Cure to Prevention: Doxycycline's Potential in Prophylaxis for Sexually Transmitted Infections.
Antibiotics (Basel)
December 2024
Department of Basic and Clinical Sciences, University of Nicosia, Nicosia 2417, Cyprus.
Over the past two decades, the global incidence of sexually transmitted infections (STIs) such as gonorrhea, chlamydia, and syphilis have increased significantly, particularly among cisgender men who have sex with men (MSM) and transgender women (TGW). This rise in STIs has spurred interest in new preventive measures, including doxycycline post-exposure prophylaxis (DoxyPEP). Clinical trials in the United States and France have demonstrated the effectiveness of DoxyPEP in reducing both chlamydia and syphilis incidence among MSM and TGW; although, its efficacy against gonorrhea remains limited, and it was further found to be ineffective among cisgender women in Kenya.
View Article and Find Full Text PDFPeritonitis After Endometrial Cytology in a Woman With Hydrosalpinx Caused by Chronic Infection.
J Med Cases
January 2025
Department of Gynecology, Tokyo Takanawa Hospital, Tokyo, Japan.
Some women infected with (CT) are asymptomatic, while others experience lower abdominal discomfort when the inflammatory process extends to the fallopian tubes. Without treatment, salpingitis can progress to pelvic peritonitis and subsequently, peritonitis in the upper abdomen, a condition known as Fitz-Hugh-Curtis syndrome, in some cases. A nucleic acid amplification assay is required for diagnosing CT infection.
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