Aim: Role of PET-CT in assessment of myocardial viability in patients with LV dysfunction.
Methods: This prospective study included 120 patients with LV dysfunction who underwent 99mTechnetium-Sestamibi myocardial perfusion SPECT-CT and 18FFDG cardiac PET-CT. They also underwent serial echocardiography and coronary angiography along with myocardial perfusion and FDG PET study.
Results: Thirty-three patients had single vessel disease, 48 had triple vessel disease, and rest had double vessel disease. Among 786 segments, matched defects were seen in 432 (55%) and mismatched defects in 354 (45%) segments. 78 patients were surgically managed, and 42 were medically managed. The change in LVEF after surgical management was statistically significant compared to medical management.
Conclusion: Viability assessment should be performed in patients who present after 12h of acute myocardial infarction or with LV dysfunction due to ischemic heart disease to decide upon appropriate surgical management.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079123 | PMC |
| http://dx.doi.org/10.1016/j.ihj.2015.11.017 | DOI Listing |
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