In the present prospective study, perioperative anxiety was investigated in 52 patients, who underwent transvaginal follicular centesis for IVF treatment. Also the surgical and anaesthesiological procedures are described. The mean age of the patients was 32.2 years, and the mean period of desire for children 9.1 years. On average, six stimulation cycles were carried out. In an operation with a duration of approx. 20 minutes, an average of six oocytes were collected. As an alternative to general anaesthesia, an analgosedation, given intravenously with midazolam (0.1 mg/kg) and fentanyl (2 micrograms/kg) has been described. This necessitates continuous anaesthesiological monitoring due to respiratory depression, induced by the risk of medication. In our study, IVF patients who had a long history of desire for children, in some cases with several previous operations, show a low to moderate anxiety level before the operation. "Hospital routine" has evidently led to this low anxiety level, which is maintained after the operation.

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