In the present prospective study, perioperative anxiety was investigated in 52 patients, who underwent transvaginal follicular centesis for IVF treatment. Also the surgical and anaesthesiological procedures are described. The mean age of the patients was 32.2 years, and the mean period of desire for children 9.1 years. On average, six stimulation cycles were carried out. In an operation with a duration of approx. 20 minutes, an average of six oocytes were collected. As an alternative to general anaesthesia, an analgosedation, given intravenously with midazolam (0.1 mg/kg) and fentanyl (2 micrograms/kg) has been described. This necessitates continuous anaesthesiological monitoring due to respiratory depression, induced by the risk of medication. In our study, IVF patients who had a long history of desire for children, in some cases with several previous operations, show a low to moderate anxiety level before the operation. "Hospital routine" has evidently led to this low anxiety level, which is maintained after the operation.
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http://dx.doi.org/10.1055/s-2008-1026677 | DOI Listing |
BMC Pregnancy Childbirth
January 2025
Reproductive Obstetrics and Gynecology Center of the Second Affiliated Hospital, Nanjing Medical University, 210028, Nanjing, China.
Background: The safety and effectiveness of short-term insemination remain a subject of controversy. This study aims to investigate the impact of short-term insemination on both embryo quality and pregnancy outcomes and whether it is necessary to apply short-term insemination to all patients underwent in vitro fertilization (IVF).
Methods: A retrospective analysis was conducted on 3,496 patients from two centers over the period January 2016 to December 2022.
J Assist Reprod Genet
January 2025
Department of Assisted Reproductive Medicine, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, 2699nd West Gao Ke Road, Shanghai, 201204, China.
Purpose: Women with polycystic ovary syndrome (PCOS) show greater heterogeneity in ovarian responses during ovarian stimulation. We aimed to investigate the potential predicting factors among individualized basic parameters that affect poor or hyper ovarian responses in PCOS patients.
Methods: We retrospectively screened 2058 women with PCOS who underwent their first cycle of in vitro fertilization/intracytoplasmic sperm injection.
Aim: Within the in vitro fertilization (IVF) process, to evaluate the possibility of using the state of the meiotic spindle of oocytes as an indicator of maturity in order to optimize the timing of vitrification.
Patients And Methods: In the presented report, the cause of couple infertility was a combination of a 38-year-old female and 43-year-old male with azoospermia, which was an indication for oocyte vitrification. Oocyte polar bodies and optically birefringent meiotic spindles were visualized by polarized light microscopy and their states and relative positions were used as indicators of oocyte maturation, i.
Objective: We aimed to compare highly purified human menopausal gonadotropin (hp-hMG) and recombinant follicle stimulating hormone (rFSH) in short antagonist in vitro fertilization (IVF) cycles of patients with poor ovarian reserve (POR). Limited research exists on this comparison in short antagonist cycles for this patient group.
Materials And Methods: This retrospective cohort study involved 165 POR patients aged 18-45 years who underwent IVF between 2018 and 2022.
Urology
January 2025
Glickman Urological and Kidney Institute, Cleveland Clinic Foundation, Cleveland, OH.
Objectives: To determine if routine pre-vasectomy sperm cryopreservation is more cost-effective than fertility restoration for patients who desire additional children following vasectomy?
Methods: A scoping review was performed to collect published data regarding efficacy and outcomes of cryopreservation, vasectomy reversal, surgical sperm retrieval, and assisted reproductive technologies (ART). Cost data were collected from US-based facilities performing cryopreservation and andrology clinical care. A cost-effectiveness model was generated using TreeAge Pro cost-effectiveness modeling software with three different variations representing a balanced scenario with median expected parameter values, a scenario with assumptions/variables favoring pre-vasectomy cryopreservation, and a scenario favoring fertility restoration.
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