AI Article Synopsis
- A new variant of atypical type A thymoma was classified by the WHO in 2015.
- A 72-year-old woman had a large mediastinal mass that was diagnosed as non-invasive thymoma prior to surgery.
- Post-surgery, the tumor was confirmed as an atypical type A thymoma variant, emphasizing the challenge of preoperative diagnosis and the need for careful follow-up.
Article Abstract
Background: An atypical type A thymoma variant was newly added to the WHO classification of type A thymoma family in 2015.
Case Presentation: A 72-year-old female was present a large round mass in the anterior mediastinum. The radiological examination led to a preoperative diagnosis of non-invasive thymoma. Tumor resection was undertaken via median sternotomy. Complete removal of the mediastinal tumor was achieved. Pathological examination revealed that the tumor cells were spindle- and oval-shaped with atypia. Immunohistochemical work-up revealed that the tumor was type A thymoma. On the basis of these findings, the tumor was finally diagnosed to be an atypical type A thymoma variant.
Conclusions: Preoperative diagnosis as atypical type A thymoma variant based on radiological examination is difficult. In case of atypical type A thymoma variant, a careful postoperative systemic follow-up should be done.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074948 | PMC |
| http://dx.doi.org/10.1186/s40792-016-0245-3 | DOI Listing |
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