Phosphatidylinostitol-3-kinase (PI3K) is the potential anticancer target in the PI3K/Akt/ mTOR pathway. Here we reviewed the ATP-competitive small molecule PI3K inhibitors in the past few years, including the pan Class I PI3K inhibitors, the isoform-specific PI3K inhibitors and/or the PI3K/mTOR dual inhibitors.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351699 | PMC |
| http://dx.doi.org/10.18632/oncotarget.12742 | DOI Listing |
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