Objective: We established test-retest reliability of electrodermal markers used to quantify physiological response to sensation using the Sensory Challenge Protocol in children with and without autism spectrum disorder (ASD).
Method: Electrodermal activity (EDA) was measured during rest and in response to sensory inputs. Fourteen children with ASD and 18 typically developing children were tested and retested after 2-6 wk on skin conductance response, skin conductance level, nonspecific skin conductance response, and habituation.
Results: Test-retest reliability was evaluated with intraclass correlation coefficients (ICCs). Rest-phase coefficients for both groups were moderate (.65-.73). ICCs during response to sensation ranged from moderate to good for amplitude (.60-.81) and magnitude (.50-.75). In addition, moderate to excellent reliability (.51-.93) was observed for nonspecific response measures.
Conclusion: EDA measures are reliable physiological markers that can quantify response to sensation in children with and without ASD.
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http://dx.doi.org/10.5014/ajot.2016.018291 | DOI Listing |
Clin Oral Investig
January 2025
Department of Endodontics, Guangdong Engineering Research Center of Oral Restoration and Reconstruction, Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Affiliated Stomatology Hospital of Guangzhou Medical University, Guangzhou, China.
Objectives: We investigated the recently generated RNA-sequencing dataset of pulpitis to identify the potential pain-related lncRNAs for pulpitis prediction.
Materials And Methods: Differential analysis was performed on the gene expression profile between normal and pulpitis samples to obtain pulpitis-related genes. The co-expressed gene modules were identified by weighted gene coexpression network analysis (WGCNA).
Front Public Health
January 2025
Department of GSpine4, IRCCS Ospedale Galeazzi-Sant'Ambrogio, Milan, Italy.
Background: Musculoskeletal pain represents an increase in medical expenses due to disability and decreased quality of life among workers. Various biopsychosocial factors contribute to the development of persistent and disabling musculoskeletal pain. The Prevent for Work questionnaire (P4Wq) intended to analyze these factors.
View Article and Find Full Text PDFFront Neuroanat
January 2025
Department of Anatomy, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.
Neuropathic pain is a pervasive health concern worldwide, posing significant challenges to both clinicians and neuroscientists. While acute pain serves as a warning signal for potential tissue damage, neuropathic pain represents a chronic pathological condition resulting from injury or disease affecting sensory pathways of the nervous system. Neuropathic pain is characterized by long-lasting ipsilateral hyperalgesia (increased sensitivity to pain), allodynia (pain sensation in response to stimuli that are not normally painful), and spontaneous unprovoked pain.
View Article and Find Full Text PDFSci Rep
January 2025
HUN-REN-ELTE Comparative Ethology Research Group, Budapest, Hungary.
Most studies on dogs' olfactory performance focused only on some individuals pre-trained for a task or on specially selected/trained detection dogs. Here, using the Natural Detection Task (NDT) that does not require training, we assessed the effect of several potential factors on the performance of a large sample of dogs (N = 527/tested, 484/analysed). Olfactory success was associated with breeds, but breed groups (selected for olfaction, cooperation, or both) were proven non-relevant, suggesting that breed-specific traits are more influential than functional breed group characteristics.
View Article and Find Full Text PDFJ Physiol Sci
January 2025
Thermal Biology Research Group, Nagoya Advanced Research and Development Center, Nagoya City University, Nagoya, Japan.
Human skin, as a sophisticated sensory organ, is able to detect subtle changes in ambient temperature. This thermosensory capability is primarily mediated by temperature-sensitive TRP channels expressed in both sensory neurons and keratinocytes. Among these, TRPV3, which responds to warm temperatures and plays a crucial role in various skin functions, is particularly notable.
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