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| http://dx.doi.org/10.1016/j.jdcr.2016.08.005 | DOI Listing |
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Disseminated Cryptococcosis in an HIV-Negative Patient With Liver Cirrhosis and Asplenia: A Rare but Dreadful Disease.
Cureus
April 2023
Hospital Medicine, University of Florida Health, Jacksonville, USA.
Cryptococcosis (cryptococcal infection) is a severe life-threatening fungal infection. It is seen worldwide, specifically in immunocompromised, mainly in human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS)-infected individuals. Cryptococcal infection can present with meningitis, pneumonia, peritonitis, disseminated cryptococcosis, and cryptococcal fungemia.
View Article and Find Full Text PDFOptic Perineuritis Associated With Cryptococcal Meningitis Presenting With a "Hot Orbit" in a Patient With Chronic Lymphocytic Leukemia.
J Neuroophthalmol
June 2022
Department of Ophthalmology (DLL, BKC, EDG), Mass Eye and Ear, Boston, Massachusetts; Department of Ophthalmology (EKT), Boston Medical Center, Boston, Massachusetts; Department of Pathology (MYL), Boston VA Medical Center, Boston, Massachusetts; Department of Optometry (JEK), Boston VA Medical Center, Boston, Massachusetts; Department of Radiology (NJF), Stanford University Medical Center, Stanford, California; Department of Ophthalmology (DRL), Boston VA Medical Center, Boston, Massachusetts; Division of Ophthalmic Plastic and Reconstructive Surgery (DRL), Massachusetts Eye and Ear, Boston, Massachusetts; Division of Neuro-Immunology (BKC), Massachusetts General Hospital, Boston, Massachusetts; Department of Ophthalmology (EDG), Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts; and Picower Institute for Learning and Memory (EDG), Massachusetts Institute of Technology, Cambridge, Massachusetts.
Article Synopsis
- A 75-year-old man experienced worsening left eye pain, swelling, and difficulty moving his eye, with a medical history of diabetes and chronic lymphocytic leukemia.
- Imaging showed significant swelling and changes around his optic nerve, leading to a diagnosis of orbital cellulitis initially.
- Further tests revealed he had cryptococcal meningitis causing optic nerve inflammation, but after a month of antifungal treatment, his symptoms improved despite challenges from immune reconstitution inflammatory syndrome.
Rare manifestation of ocular immune reconstitution inflammatory syndrome from infection in a patient with AIDS.
Int J Mycobacteriol
October 2021
Department of Ophthalmology, Phramongkutklao Hospital, Bangkok, Thailand.
Immune reconstitution inflammatory syndrome (IRIS) is a common complication following the initiation of antiretroviral therapy (ART). The most commonly associated pathogens include Mycobacterium tuberculosis and Cryptococcus spp. IRIS following nontuberculosis mycobacteria (NTM) infection is uncommon, particularly, IRIS following NTM conjunctivitis.
View Article and Find Full Text PDFMediastinal Small Cell Carcinoma with Primary Cutaneous Cryptococcosis: A Rare Case Report.
Infect Drug Resist
September 2021
Department of Dermatology, The Second Hospital of Dalian Medical University, Dalian, Liaoning, People's Republic of China.
Cutaneous cryptococcosis, an infectious disease resulting from , primarily affects immunodeficient individuals. Here, we report a case of mediastinal small cell carcinoma (MSCC) complicated with multiple skin and soft tissue infections mimicking erysipelas and cellulitis. Antibiotics for bacteria were ineffective and a culture of pus from the infected areas revealed in this patient.
View Article and Find Full Text PDFDisseminated Cryptococcosis Presenting as Cellulitis Diagnosed by Laser Capture Microdissection: A Case Report and Literature Review.
Mycopathologia
June 2021
Department of Dermatology and Venerology, Peking University First Hospital, 8 Xishiku Street, Xicheng District, Beijing, 100034, China.
Disseminated cryptococcosis primarily affects immunosuppressed patients and has a poor outcome if diagnosis and treatment are delayed. Skin lesions are rarely manifest causing misdiagnosis. We present a case of cryptococcal cellulitis with severe pain in a kidney transplant recipient on long-term immunosuppressive therapy.
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