AI Article Synopsis
- There's been a significant increase in reports about synthetic methods that activate sp and sp C-H bonds, showing their potential as effective synthetic tools.
- These methods are particularly useful for forming C-C and C-heteroatom bonds, offering fresh approaches to creating new pharmaceuticals.
- The text discusses recent innovative C-H activation processes that demonstrate how these techniques can be valuable in medicinal chemistry.
Article Abstract
In recent years, there has been an exponential rise in the number of reports describing synthetic methods that utilize catalytic sp and sp C-H bond activation. Many have emerged as powerful synthetic tools for accessing biologically active motifs. Indeed, application to C-C and C-heteroatom bond formation, provides new directives for the construction of new pharmaceutical entities. Herein, we highlight some recent novel C-H activation processes that exemplify the utility of these transformations in medicinal chemistry.
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| http://dx.doi.org/10.1016/j.bmcl.2016.06.036 | DOI Listing |
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