The acquisition of methicillin-resistant Staphylococcus aureus (MRSA) after exposure to patients colonized or infected with MRSA was assessed. Among contacts with complete surveillance screening, the rate of acquisition was 5.7% and was lower in those identified postdischarge (17/683, 2.5%) compared with those tested in the immediate postexposure period (62/706, 8.8%).
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http://dx.doi.org/10.1016/j.ajic.2016.09.009 | DOI Listing |
Cell Mol Biol (Noisy-le-grand)
January 2025
Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.
Antibiotics play a fundamental role in protecting millions of lives from infectious diseases. However, an important drawback of antibiotic treatment is that each advancement was followed by the development of resistance. This is due to the fact that the majority of pathogenic bacteria are capable of becoming resistant to a number of antimicrobial agents.
View Article and Find Full Text PDFFood Chem
December 2024
Department of Clinical Laboratory, The Children's Hospital, Zhejiang University School of Medicine, Hangzhou 310052, China; Binjiang Institute of Zhejiang University, Hangzhou 310053, China. Electronic address:
Antibiotic-resistant bacteria pose considerable risks to global health, particularly through transmission in the food chain. Herein, we developed the artificial intelligence-driven quantification of antibiotic-resistant bacteria in food using a color-encoded multiplex hydrogel digital loop-mediated isothermal amplification (LAMP) system. The quenching of unincorporated amplification signal reporters (QUASR) was first introduced in multiplex digital LAMP.
View Article and Find Full Text PDFOne Health
December 2024
ANSES - Université de Lyon, Unité Antibiorésistance et Virulence Bactériennes, Lyon, France.
The gene conferring methicillin-resistance has always been found on a SCC type XI element and is largely restricted to the few clonal complexes CC130, CC1943, CC425, CC49 and CC599. The occurrence of the gene in many different hosts highlighted its One Health importance, even though European hedgehogs () are considered its natural reservoir, most probably because of the selective pressure imposed by beta-lactam-producing dermatophytes () that colonize the skin of these mammals. Surprisingly, while the presence of on the French territory has been proven, no -positive methicillin-resistant (MRSA) isolate has been reported yet from hedgehogs.
View Article and Find Full Text PDFJ Microbiol Immunol Infect
November 2024
Division of Pediatric Infectious Diseases, Chang Gung Memorial Hospital, 333, Taoyuan, Taiwan; Molecular Infectious Diseases Research Center, Chang Gung Memorial Hospital, 333, Taoyuan, Taiwan; Chang Gung University School of Medicine, 333 Taoyuan, Taiwan. Electronic address:
Background: Recurrent or persistent methicillin-resistant Staphylococcus aureus (MRSA) bacteremia presents significant clinical challenges. Comprehensive genomic-scale studies on the genetic changes in MRSA that correspond to refractory bacteremia are lacking.
Method: From 2011 to 2019, MRSA blood isolates were collected from patients with persistent or recurrent bacteremia at a teaching hospital in southern Taiwan.
Drug Resist Updat
January 2025
State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; Jinan Microecological Biomedicine Shandong Laboratory, Jinan, China; Research Units of Infectious Disease and Microecology, Chinese Academy of Medical Sciences, Beijing, China. Electronic address:
Background: Long-term comprehensive studies on the genomic epidemiology of both methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-susceptible S. aureus (MSSA) isolates are limited in China. Here, we aimed to assess the genomic epidemiological characteristics and population dynamics of S.
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