Three new limonoid-type triterpenoids, namely toonasins A-C (1-3) with a rare lactam E ring, along with six known compounds (4-9) were isolated from the barks of Toona sinensis. The structures of new compounds were elucidated by interpretation of spectroscopic data, and the relative configuration of compound 1 was further characterized by X-ray crystallographic analyses. The isolated compounds were evaluated for their cytotoxic activities against five human tumor cell lines (HL-60, SMMC-7721, A-549, MCF-7 and SW480), and compounds 3 and 5 showed weak cytotoxicities.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080210 | PMC |
| http://dx.doi.org/10.1007/s13659-016-0108-4 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Mitigation of high-fat diet-induced sarcopenia by fruit extracts via autophagic flux and mitochondrial quality control.
Food Sci Biotechnol
January 2025
Department of Life Sciences, College of Bioscience and Biotechnology, National Cheng Kung University, Tainan, 70101 Taiwan.
Unlabelled: Sarcopenic obesity, encompassing both muscle wasting and obesity, is relevant across individuals. (TS) has been shown to regulate glucose and lipid metabolisms. However, the efficacy and mechanisms of TS fruit (TSF) in sarcopenic obesity are unclear.
View Article and Find Full Text PDFPopulation structure and genetic diversity of Toona sinensis revealed by whole-genome resequencing.
BMC Genom Data
January 2025
Key Laboratory of State Forestry and Grassland Administration Conservation and Utilization of Warm Temperate Zone Forest and Grass Germplasm Resources, Shandong Provincial Center of Forest and Grass Germplasm Resources, Ji'nan, 250103, Shandong, China.
Objectives: Toona sinensis, commonly known as Chinese toon, is a perennial woody plant with significant economic and ecological importance. This study employed whole-genome resequencing of 180 T. sinensis samples collected from Shandong to analyze genetic variation and diversity, ultimately identifying 18,231 high-quality SNPs after rigorous quality control and linkage disequilibrium pruning.
View Article and Find Full Text PDFLong-Term Conservation Agriculture Improves Soil Quality in Sloped Farmland Planting Systems.
Plants (Basel)
December 2024
College of Environment, Hohai University, Nanjing 210098, China.
Conservation agriculture practices (CAs) are important under the increasingly serious soil quality degradation of sloping farmlands worldwide. However, little is known about how the long-term application of CAs influences soil quality at different slope positions. We conducted field experiments for a watershed sloping farmland's mainstream planting systems in the Three Gorges Reservoir area of China.
View Article and Find Full Text PDFPurification and Characterization of γ-Glutamyl Transpeptidase from and Its Function on Formation of Sulfur-Containing Volatiles.
J Agric Food Chem
November 2024
School of Nutrition and Food Sciences, Louisiana State University, Baton Rouge Louisiana 70803, United States.
γ-Glutamyl transpeptidase (GGT) in shoot (TS) was extracted and purified through salt precipitation, ion-exchange column, and gel filtration chromatography methods. The GGT had two peptides with M.W.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!