Pan-spinal infection: a case series and review of the literature.

J Spine Surg

Department of Neurosurgery, Alfred Hospital; ; Department of Surgery, Monash University, Melbourne, Australia.

Published: September 2016

Background: Panspinal infection usually presents with fever, back pain, neurological deficit, and in advanced cases multi-organ failure and septic shock. The choice of treatment for panspinal infection is challenging because these patients are usually medically unstable with severe neurological compromise. The objective of this study is to review management and long term outcomes for patients with panspinal infection.

Methods: A retrospective review of patients with panspinal infection treated in our center over a 5-year period [Jan 2010-Dec 2014] and a review of the current published literatures was undertaken.

Results: We identified 4 patients with panspinal infection. One case was managed medically due to high perioperative risk, whilst the other three were managed surgically whilst on antibiotic therapy. All 3 cases managed surgically improved neurologically and infection subsided, whereas the patient managed medically did not change neurologically and infection subsided.

Conclusions: Patients with panspinal infection should be treated surgically unless the medical risk of surgery or anaesthesia is prohibitive.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067279PMC
http://dx.doi.org/10.21037/jss.2016.08.04DOI Listing

Publication Analysis

Top Keywords

panspinal infection
20
patients panspinal
16
infection case
8
infection treated
8
managed medically
8
managed surgically
8
neurologically infection
8
infection
7
panspinal
6
patients
5

Similar Publications

Background: SEAs are infrequent; however, panspinal infections are even rarer, especially when GBS infection is involved. The cornerstone of treatment is based on early diagnosis and use of targeted antimicrobial therapy; in case of cord compression or neurological compromise, urgent surgical intervention should be pursued. Overall, it is an infrequent condition and therefore requires prospective multicenter studies.

View Article and Find Full Text PDF

Panspinal epidural abscesses are an extremely rare yet potentially fatal condition. Whether cases are best managed surgically or medically is currently controversial. A 63-year-old patient with diabetes presented initially with abdominal pain, back pain, urinary retention and constipation.

View Article and Find Full Text PDF

Background: Rapid progression of metastatic non-small cell lung cancer (NSCLC) after discontinuation of tyrosine kinase inhibitors or anaplastic lymphoma kinase (ALK) inhibitors has been described and is associated with a poor prognosis. We describe the first reported case of accelerated NSCLC tumor extension throughout the entire spinal epidural space.

Case Description: A 68-year-old woman with stage IV ALK-positive metastatic NSCLC presented with acute neck pain, urinary retention, and lower extremity weakness 15 days post discontinuation of alectinib.

View Article and Find Full Text PDF

Background: Subdural empyema can present as a spinal subdural empyema (SSE) or a cranial subdural empyema (CSE). Although they differ somewhat in epidemiology, etiology, pathophysiology, and symptomatology and occur separately, they rarely manifest together. The aim of this article is to review the literature concerning the clinical presentation, clinical course, and treatment options for managing concurrently occurring SSE and CSE.

View Article and Find Full Text PDF

Holospinal epidural abscesses - Institutional experience.

J Clin Neurosci

February 2018

Department of Neurological Surgery, Oregon Health & Science University, Portland, OR, United States. Electronic address:

Purpose: The authors present a holospinal epidural abscesses (HEA) case series and a single institution's experience with varied surgical approaches and outcomes.

Methods: Medical records were queried and reviewed (6 years) for patients with a spinal abscess diagnosis; HEA were selected. Medical history, comorbidities, blood and epidural pathogens, presentation symptoms, abscess location, presence of mass effect, surgical procedures, treatment regimens, and neurological outcomes were collected.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!