Aim: To evaluate the phenolics composition and inhibitory effect of the leaves extracts of and on two key enzymes (pancreatic lipase [PL] and angiotensin 1-converting enzyme [ACE]) involved in obesity and hypertension .
Materials And Methods: The phenolics (flavonoids and phenolic acids) were quantified using high-performance liquid chromatography coupled with diode array detection. PL and ACE inhibitory effects; DPPH* and ABTS* scavenging activities of the extracts were tested using spectrophotometric methods.
Results: had the following major phenolics: Rutin, quercetin, and quercitrin (flavonoids); caffeic, chlorogenic, and gallic acids (phenolic acids); while had the following major phenolics: Rutin, quercitrin, and luteolin (flavonoids); ellagic and chlorogenic acids (phenolic acids). "Extracts of both plants inhibited PL and ACE; scavenged DPPH* in a dose-dependent manner". extract was more potent in inhibiting PL (IC 20.69 µg/mL) and ACE (IC 29.44 µg/mL) than (IC 52.14 µg/mL and IC 64.99 µg/mL, against PL and ACE, respectively). also scavenged DPPH* and ABTS* more than .
Conclusion: and leaves could be used as functional foods for the management of obesity and obesity-related hypertension. However, may be more effective than .
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| http://dx.doi.org/10.5455/jice.20160814112756 | DOI Listing |
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