The use of therapeutic hypothermia in the management of amniotic fluid embolism.

Obstet Med

Department of Obstetrics and Gynecology, Rush Medical Center, Chicago, IL, USA.

Published: June 2013

Background: Amniotic fluid embolism (AFE) is a rare peripartum obstetric emergency where patients seldom survive neurologically intact. The exact pathophysiology is not completely understood and treatment remains mainly supportive.

Case: A 34-year-old African American woman gravida 1, para 0-0-0-0 at 38 weeks and four days induced for chronic hypertension with superimposed preeclampsia experienced an AFE during labour. Supportive treatment included early use of therapeutic hypothermia resulting in a normal neurological outcome.

Conclusion: This case demonstrates the timely use of therapeutic hypothermia in a patient surviving an AFE and suffering no neurological sequelae. Therapeutic hypothermia should be considered in the supportive treatment of AFE.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052767PMC
http://dx.doi.org/10.1258/OM.2011.110069DOI Listing

Publication Analysis

Top Keywords

therapeutic hypothermia
16
amniotic fluid
8
fluid embolism
8
supportive treatment
8
therapeutic
4
hypothermia management
4
management amniotic
4
embolism background
4
background amniotic
4
afe
4

Similar Publications

The impact of clinical seizures and adverse brain MRI patterns in neonates with hypoxic-ischemic encephalopathy and abnormal neurodevelopment.

Clinics (Sao Paulo)

January 2025

Department of Pediatrics, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea. Electronic address:

Introduction: This study aimed to investigate the associations among seizures, clinical characteristics, and brain injury on Magnetic Resonance Imaging (MRI) in infants with Hypoxic Ischemic Encephalopathy (HIE), and to determine whether these findings can predict unfavorable neurodevelopmental outcomes.

Method: Clinical and electrographic seizures were assessed by amplitude-integrated electroencephalogram, and the extent of brain injury was evaluated by using MRI. At 12‒24 months of age, developmental impairment or death was assessed.

View Article and Find Full Text PDF

Therapeutic hypothermia in preterm infants under 36 weeks: Case series on outcomes and brain MRI findings.

Eur J Pediatr

January 2025

Neonatology Department. Hospital Sant Joan de Déu, Center for Maternal Fetal and Neonatal Medicine. Neonatal Brain Group, Universitat de Barcelona. Hospital Clínic, Universitat de Barcelona. BCNatal - Barcelona, Institut de Recerca Sant Joan de Déu, Barcelona, Spain.

Purpose: Perinatal hypoxic-ischemic encephalopathy (HIE) is a significant cause of neonatal brain injury. Therapeutic hypothermia (TH) is the standard treatment for term neonates, but its safety and efficacy in neonates < 36 weeks gestational age (GA) remains unclear. This case series aimed to evaluate the outcomes of preterm infants with HIE treated with TH.

View Article and Find Full Text PDF

Mild therapeutic hypothermia after cardiac arrest: effect on survival with good neurological outcome outside of randomised controlled trials: A registry-based analysis.

Eur J Anaesthesiol

February 2025

From the Department of Neurosurgery, University of Buenos Aires School of Medicine (FZ), Department of Critical Care, Clínica Sagrada Familia (MR) and Department of Critical Care, Hospital Eva Perón de Merlo, Buenos Aires Province, Argentina (FZ, WV).

View Article and Find Full Text PDF

Identification of the MAP4K gene family reveals GhMAP4K13 regulates drought and salt stress tolerance in cotton.

Physiol Plant

January 2025

Zhengzhou Research Base, State Key Laboratory of Cotton Bio-breeding and Integrated Utilization, School of Agricultural Sciences, Zhengzhou University, Zhengzhou, China.

Mitogen-activated protein kinase kinase kinase kinases (MAP4Ks) are a class of highly conserved serine/threonine-protein kinases in eukaryotes. They participate in the typical MAPK cascade system and various signal transduction pathways regulating biological processes in plants, during stressful conditions. To date, genome-wide identification of MAP4Ks in cotton has not been reported.

View Article and Find Full Text PDF

Background: ST-segment elevation myocardial infarction (STEMI) is treated with immediate primary percutaneous coronary intervention (pPCI) to restore coronary blood flow in the acutely ischaemic territory, but is associated with reperfusion injury limiting the benefit of the therapy. No treatment has proven effective in reducing reperfusion injury. Transcoronary hypothermia has been tested in clinical studies and is well tolerated, but is generally established after crossing the occlusion with a guidewire therefore after initial reperfusion, which might have contributed to the neutral outcomes.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!