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Clinical Significance of MRI-Based Measurements of Tibial Plateau Widening Width and Joint Fluid Volume During Anterior Cruciate Ligament Injuries Among Patients With Tibial Plateau Fractures.
Ann Ital Chir
March 2025
Department of Pediatrics, Mianzhu People's Hospital, 618200 Mianzhu, Sichuan, China.
Aim: This study aimed to explore the diagnostic value of magnetic resonance imaging (MRI)-based tibial plateau widening width (TPW) and joint effusion volume during anterior cruciate ligament (ACL) injuries among patients with tibial plateau fractures.
Methods: This retrospective study collected clinical data from 100 patients with tibial plateau fractures admitted between February 2022 and February 2024. The findings from arthroscopy or surgical intervention served used as the "gold standard".
Assessment of knowledge, attitudes, and performance of postgraduate nursing students regarding clinical reasoning and evidence-based nursing: a multicenter cross-sectional study in Iran.
BMC Nurs
March 2025
Department of Medical Surgical Nursing, School of Nursing, Fasa University of Medical Sciences, Fasa, Iran.
Background: Within the realm of medical education, particularly in nursing, the paramount objective is to cultivate professionals who can make optimal clinical decisions through the integration of critical thinking skills, comprehensive knowledge, clinical reasoning, and evidence-based nursing practices. Given that these professional competencies constitute the cornerstone of effective healthcare delivery; their systematic development has become increasingly imperative. This study, therefore, aims to evaluate postgraduate nursing students' knowledge, attitudes, and performance regarding clinical reasoning and evidence-based nursing.
View Article and Find Full Text PDFAssociations of depressive symptoms and cortisol with cognitive performance among memory clinic patients.
Int Psychogeriatr
March 2025
Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences, and Society, Karolinska Institutet, Stockholm, Sweden; Cognitive Disorders Clinic, Theme Inflammation and Aging, Karolinska University Hospital, Stockholm, Sweden. Electronic address:
Objective: Test the hypothesis that depressive symptoms are associated with cognitive performance and that cortisol levels may explain this association independently of Alzheimer's Disease (AD) biomarker levels.
Design: Longitudinal observational study.
Setting: Memory clinic, Karolinska University Hospital, Stockholm, Sweden.
Bioethics Artificial Intelligence Advisory (BAIA): An Agentic Artificial Intelligence (AI) Framework for Bioethical Clinical Decision Support.
Cureus
March 2025
Responsible AI, Kaiser Permanente, Oakland, USA.
Healthcare professionals face complex ethical dilemmas in clinical settings in cases involving end-of-life care, informed consent, and surrogate decision-making. These nuanced situations often lead to moral distress among care providers. This paper introduces the Bioethics Artificial Intelligence Advisory (BAIA) framework, a novel and innovative approach that leverages artificial intelligence (AI) to support clinical ethical decision-making.
View Article and Find Full Text PDFPathological expression of mitochondrial genome-derived circRNA SCAR/mc-COX2 and its ceRNA network in colorectal cancer: implications for clinical significance.
BMC Cancer
March 2025
Cellular and Molecular Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Background: Mitochondrial-encoded circular RNAs (mecciRNAs) are a newly discovered class of mitochondrial-encoded non-coding RNAs (mt-ncRNAs) that play important biological roles in the cell. This study aimed to examine the expression profile of SCAR/mc-COX2 (has_circ_0089762) in colorectal cancer (CRC) and its relationship with clinicopathological variables. Furthermore, to better understand SCAR/mc-COX2's functional role in CRC, we constructed a competing endogenous RNA (ceRNA) network.
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