AI Article Synopsis
- ERETIC2 is a quantitative NMR technique that uses PULCON methodology to measure in vivo concentrations of substances.
- The accuracy of the PULCON method was evaluated using maleic acid as a standard.
- Results showed that PULCON can effectively quantify marine toxins like okadaic acid without contamination from internal standards, matching results obtained from traditional methods.
Article Abstract
ERETIC2 (Electronic Reference To access In vivo Concentrations 2) based on PULCON (Pulse Length-based Concentration determination) methodology is a quantitative NMR (qNMR) using an external standard. The performance of the PULCON method was assessed using maleic acid (MA). Quantification of the diarrhetic shellfish toxin and okadaic acid by PULCON was successfully consistent with that obtained by a conventional internal standard method, demonstrating that the PULCON method is useful for the quantification of invaluable marine toxins without any contaminations by an internal standard.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086654 | PMC |
| http://dx.doi.org/10.3390/toxins8100294 | DOI Listing |
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