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Socioeconomic influences on stroke outcomes: A comprehensive zip code-based hospital analysis.
Clin Neurol Neurosurg
December 2024
Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA. Electronic address:
Background And Objectives: Stroke remains a leading cause of morbidity and mortality worldwide. Socioeconomic disparities significantly affect the treatment and outcomes of cardiovascular and cerebrovascular diseases, including acute ischemic stroke. This study examines patients treated at Thomas Jefferson University Hospital, with ZIP code-based socioeconomic data predominantly representing areas in Pennsylvania and New Jersey, as the majority of patients originate from these regions.
View Article and Find Full Text PDFMetabolic Tumor Volume Response after Bridging Therapy Determines Chimeric Antigen Receptor T-Cell Outcomes in Large B-Cell Lymphoma.
Clin Cancer Res
November 2024
Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York.
Article Synopsis
- Scientists wanted to see how a treatment called bridging therapy (BT) affects the success of another treatment called CAR T-cell therapy for patients with a type of cancer called large B-cell lymphoma (LBCL).
- They found that many patients who got BT showed a decrease in their cancer's size before the main treatment, which helped them do better overall.
- The study showed that patients who started with high cancer levels could end up doing just as well as those who started with low levels after getting this helpful bridging therapy.
Perioperative Outcomes and Reimbursement Patterns Associated With the Anterior versus Posterior Approach for Treatment of Type 2 Odontoid Fractures, a National Surgical Quality Improvement Program Analysis.
World Neurosurg
November 2024
Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden. Electronic address:
Objective: To evaluate the short-term surgical outcomes and the reimbursement patterns, after treatment of type 2 odontoid fractures using the anterior or posterior approach.
Methods: The National Surgical Quality Improvement Program database was queried for surgically treated patients with type 2 odontoid fractures by the anterior or posterior approach between 2016 and 2020. Propensity score matching with the optimal approach was used to balance the cohorts.
The rate of isolated locoregional recurrence after surgery for pancreatic adenocarcinoma (PDAC) approaches 25%. Ablative radiation therapy (A-RT) has improved outcomes for locally advanced disease in the primary setting. We sought to evaluate the outcomes of salvage A-RT for isolated locoregional recurrence and examine the relationship between subsequent patterns of failure, radiation dose, and treatment volume.
View Article and Find Full Text PDFImpact of the pandemic and concomitant COVID-19 on the management and outcomes of middle cerebral artery strokes: a nationwide registry-based study.
BMJ Open
February 2024
Neurosurgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
Objectives: To investigate the impact of the COVID-19 pandemic as well as concomitant COVID-19 itself on stroke care, focusing on middle cerebral artery (MCA) territory infarctions.
Design: Registry-based study.
Setting: We used the National Inpatient Sample (NIS) database, which covers a wide range of hospitals within the USA.
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