AI Article Synopsis
- This study examined the link between coffee consumption and liver enzyme levels among Korean immigrants (KIs) and indigenous Japanese (IJs).
- The analysis involved 966 subjects and utilized logistic regression to compare liver enzyme levels across different coffee intake levels and risk groups.
- Results showed that both KIs and IJs experienced significant inverse associations between coffee intake and specific liver enzymes, with no significant differences between the two ethnic groups.
Article Abstract
Objectives: Significant inverse association between coffee intake and the levels of liver enzymes has been reported. We demonstrated higher prevalence of metabolic syndrome in Korean immigrants (KIs) than in indigenous Japanese (IJs). The aim of this study was to investigate whether the association between coffee intake and liver enzyme levels was different between the 2 ethnic groups.
Methods: This study is a cross-sectional study including a total of 966 subjects comprising KIs and IJs. The association between the quintiles of coffee intake and dichotomous values of liver enzymes was evaluated by logistic regression analysis in KIs, IJs, a high-risk group (current smokers or alcohol drinkers ≥45 g/day), and a low-risk group (non-smokers and alcohol drinkers <45 g/day).
Results: In KIs, a significant inverse association between coffee intake and serum aspartate aminotransferase (AST) levels was observed. In the IJs, a significant inverse association between coffee intake and serum alanine aminotransferase levels was observed. In the high-risk group, a significant inverse association between coffee intake and serum AST and gamma-glutamyltransferase levels was observed.
Conclusion: No difference was observed between KIs and IJs regarding the association between coffee and liver enzymes. Coffee might inhibit hepatic damage by alcohol drinking and smoking.
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| http://dx.doi.org/10.1159/000448832 | DOI Listing |
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