Multifocal extranodal lymphoma: A case report.

Medicine (Baltimore)

Department of Oncology, Beijing Hospital Department of Pathology, Beijing Hospital Cancer Hospital, Chinese Academy of Medical Science Department of Nuclear Medicine, Beijing Hospital, Beijing, China.

Published: October 2016

Introduction: We report an unusual and interesting case of non-Hodgkin lymphoma involving 7 extranodal sites.In this case, a 43-year-old woman with diffuse large B-cell lymphoma, including stomach, breasts, pancreas, adrenal glands, ovary and bones, was confirmed by biopsy and positron emission tomography/computed tomography scan. The patient achieved a complete response after 2 cycles of chemotherapy with combined rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone, but subsequently developed central nervous system involvement.

Conclusion: This case illustrated the usefulness of positron emission tomography/computed tomography in diagnosis, disease staging, and assessment of response to therapy. Selection of the optimal treatment regimen is challenging and needs further research.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059066PMC
http://dx.doi.org/10.1097/MD.0000000000005029DOI Listing

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