PET-CT Post-Hepatic Radiation Changes in Gastroesophageal Adenocarcinoma.

Clin Nucl Med

From the *Diagnostic Radiology, Allegheny General Hospital, Pittsburgh, PA; and †Diagnostic Radiology, Stony Brook University, Stony Brook, NY; ‡Family Medicine and §Radiation Oncology, Allegheny General Hospital, Pittsburgh, PA.

Published: January 2017

AI Article Synopsis

  • - Initial PET-CT scan for gastroesophageal junction adenocarcinoma revealed no signs of distant spread, but a biopsy was performed during an esophagogastroduodenoscopy.
  • - After a month of radiation treatment, a follow-up PET-CT showed a decrease in the tumor size but indicated new activity in the liver, raising concerns about possible metastasis.
  • - Further imaging contradicted the metastasis concern, and a biopsy revealed that the increased activity was due to radiation-induced hepatitis rather than cancer spread.

Article Abstract

Gastroesophageal junction adenocarcinoma on esophagogastroduodenoscopy biopsy. Initial PET-CT showed no definite evidence of distant metastatic disease. One month after radiation treatment, repeat PET-CT showed interval decrease in size of gastroesophageal mass but new multifocal FDG avidity in the caudate and left hepatic lobes. Correlation with contrast-enhanced CT and US images was negative, making metastasis less likely. Ultrasound-guided biopsy confirmed radiation-induced hepatitis, which caused false positively increased FDG uptake from inflammatory changes.

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http://dx.doi.org/10.1097/RLU.0000000000001404DOI Listing

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PET-CT Post-Hepatic Radiation Changes in Gastroesophageal Adenocarcinoma.

Clin Nucl Med

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From the *Diagnostic Radiology, Allegheny General Hospital, Pittsburgh, PA; and †Diagnostic Radiology, Stony Brook University, Stony Brook, NY; ‡Family Medicine and §Radiation Oncology, Allegheny General Hospital, Pittsburgh, PA.

Article Synopsis
  • - Initial PET-CT scan for gastroesophageal junction adenocarcinoma revealed no signs of distant spread, but a biopsy was performed during an esophagogastroduodenoscopy.
  • - After a month of radiation treatment, a follow-up PET-CT showed a decrease in the tumor size but indicated new activity in the liver, raising concerns about possible metastasis.
  • - Further imaging contradicted the metastasis concern, and a biopsy revealed that the increased activity was due to radiation-induced hepatitis rather than cancer spread.
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