Tumor lysis syndrome (TLS) is a metabolic disorder that is generally associated with a malignancy leading to hyperuricemia, hyperphosphatemia, and acute kidney injury. On the other hand, we sometimes encounter these phenomena in nonmalignant disease, which has been referred to as tumor lysis-like syndrome in some studies. We herein experienced a case in which tumor lysis-like syndrome occurred in the course of therapy for eosinophilic disease of the lung, a nonmalignant disease. Even in nonmalignant disease, massive cell lysis induced by therapy can cause phenomena such as TLS or tumor lysis-like syndrome.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109574 | PMC |
| http://dx.doi.org/10.2169/internalmedicine.55.6659 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Tumor Lysis-like Syndrome in Eosinophilic Disease of the Lung: A Case Report and Review of the Literature.
Intern Med
February 2017
Division of Nephrology and Hypertension, St. Marianna University School of Medicine, Japan.
Tumor lysis syndrome (TLS) is a metabolic disorder that is generally associated with a malignancy leading to hyperuricemia, hyperphosphatemia, and acute kidney injury. On the other hand, we sometimes encounter these phenomena in nonmalignant disease, which has been referred to as tumor lysis-like syndrome in some studies. We herein experienced a case in which tumor lysis-like syndrome occurred in the course of therapy for eosinophilic disease of the lung, a nonmalignant disease.
View Article and Find Full Text PDFTumor lysis-like syndrome in a child during treatment for visceral leishmaniasis.
Int J Immunopathol Pharmacol
September 2016
Second Pediatric Department, Aristotle University of Thessaloniki, AHEPA Hospital, Greece.
A 2.5-year-old girl was admitted due to splenomegaly and pancytopenia. Laboratory analysis revealed pancytopenia and hypergammaglobulinemia, and due to the absence of fever and the relevant clinical and hematological presentation the child was initially suspected for acute lymphoblastic leukemia.
View Article and Find Full Text PDFGranulocyte colony stimulating factor-induced tumor lysis-like syndrome: leucolysis.
J BUON
November 2013
Department of Medical Oncology, Hacettepe University Institute of Oncology, Ankara, Turkey.
Lysis syndrome during therapy of visceral leishmaniasis.
Infection
April 2012
Department of Internal Medicine, University of Ioannina Medical School, Ioannina, Greece.
Introduction: Lysis syndrome is a constellation of metabolic disorders usually seen after the initiation of chemotherapy for rapidly proliferating malignancies (tumor lysis syndrome). Reported herein is a tumor lysis-like syndrome after the initiation of anti-infective therapy for visceral leishmaniasis.
Patients And Methods: Ten consecutive patients with visceral leishmaniasis were administered liposomal amphotericin B.
A tumor lysis-like syndrome during therapy of visceral leishmaniasis.
Ann Clin Lab Sci
April 2003
Department of Internal Medicine, University of Ioannina, Ioannina, Greece.
Reported herein for the first time in the literature is the case of a 41-yr-old woman who developed a tumor lysis-like syndrome, consisting of hyperkalemia, hyperphosphatemia, hyperuricemia, and acute renal insufficiency, soon after the initiation of chemotherapy for severe visceral leishmaniasis with liposomal amphotericin B. Allopurinol therapy, together with iv fluid administration and urine alkalization, resulted in full recovery of the metabolic abnormalities. Awareness of this condition can lead to prophylactic treatment as well as the early recognition and management of susceptible patients.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!