AI Article Synopsis
- Inbreeding depression leads to reduced fitness due to genetic factors and affects many species more significantly than previously known.
- Genomic data helps identify inbreeding depression and understand its genetic basis better.
- While strategies like purging and genetic rescue can help mitigate fitness decline, they carry their own risks and are not foolproof solutions against severe inbreeding depression.
Article Abstract
Inbreeding depression, the reduction of fitness caused by inbreeding, is a nearly universal phenomenon that depends on past mutation, selection, and genetic drift. Recent estimates suggest that its impact on individual fitness is even greater than previously thought. Genomic information is contributing to its detection and can enlighten important aspects of its genetic architecture. In natural populations, purging and genetic rescue mitigate fitness decline during inbreeding periods, and might be critical to population survival, thus, both mechanisms should be considered when assessing extinction risks. However, deliberate purging and genetic rescue involve considerable risk in the short and medium term, so that neither appears to be a panacea against high inbreeding depression.
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| http://dx.doi.org/10.1016/j.tree.2016.09.005 | DOI Listing |
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