Objective: The aim of this study was to assess the prevalence of metabolic syndrome (MS) and its association with coronary artery disease (CAD) among an elderly urban population in south India.
Methods: Individuals aged ≥60 years (n=222) were recruited from Phase 3 of the Chennai Urban Rural Epidemiology Study. Anthropometric and blood pressure measurements, oral glucose tolerance test, lipids and fasting insulin were carried out. Prevalence of MS was estimated using the World Health Organization (WHO), Modified National Cholesterol Education Program's Adult Treatment Panel III (ATP-III) and International Diabetes Federation (IDF) criteria. Diagnosis of CAD was made by resting 12 lead ECG and/or past history of documented myocardial infarction.
Results: MS was identified in 45.9% (n=102) by modified ATP-III, 37.4% (n=83) by IDF and 45.5% (n=101) by WHO criteria respectively. Only 61 subjects (27.5%) were identified by all the three criteria. Female subjects had a significantly higher prevalence of MS compared to their male counterparts (45.8 vs, 31.0%, p=0.023 respectively) according to IDF criteria. It was observed that 59.8%, 53% and 45.6% of the subjects had all five abnormalities according to modified ATP-III, IDF and WHO, respectively. Subjects with MS had significantly higher prevalence of CAD compared to those without MS using all the 3 criteria (modified ATP-III -20.6 vs.8.5%; IDF-20.5 vs.10.1%; WHO-19.8 vs.9.1% respectively). The odds ratio of developing CAD among MS subjects was 2.93, 2.39 and 2.48 compared to those without MS after adjusting for age, gender and family history of diabetes according to modified ATP-III, IDF and WHO, respectively.
Conclusions: Nearly 40% of the elderly urban south Indians have MS and it is strongly associated with CAD.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Prevalence of hyperlipidemia in psoriatic arthritis patients in Riyadh, Saudi Arabia.
Saudi Med J
December 2024
From the Internal Medicine and Rheumatology Department (AlTalhi), King Abdulaziz Specialist Hospital, Taif; from the Rheumatology Department, Prince Mohammed bin Abdulaziz Hospital (Otaywi, Alhamzi, Makkawy); from the Internal Medicine And Rheumatology Department (Alrashedi, Alokaily), Prince Sultan Military Medical City, Riyadh; from the Internal Medicine (Alotaibi), Shaqra University, Shaqra, Kingdom of Saudi Arabia.
Objectives: To estimate the prevalence of hyperlipidemia in patients with psoriatic arthritis (PsA) in Riyadh, Saudi Arabia, and to investigate the relationship between PsA and hyperlipidemia.
Methods: This retrospective study examined medical records of PsA patients from January 2010 to May 2023 at 2 medical centers in Riyadh. Patients over 18 years old with a lipid profile were included.
Impact of high-sensitivity C-reactive protein on metabolic syndrome in an elderly population: Findings from a hospital-based cross-sectional study in J&K, India.
J Family Med Prim Care
October 2024
Department of Surgery, Government Medical College, Baramulla, Jammu and Kashmir, India.
Background: Due to affluent lifestyles, primary care physicians are concerned about metabolic syndrome (MetS). Inflammation and insulin resistance are caused by extra adipose tissue. Our study seeks to evaluate, taking into account numerous variables, the relationship between high-sensitivity C-reactive protein (hsCRP) levels and MetS in adults aged 50+ in Northern Kashmir, India.
View Article and Find Full Text PDFPrevalence and determinants of dyslipidemia in 2338 Dutch childhood cancer survivors: a DCCS-LATER 2 study.
Eur J Endocrinol
November 2024
Department of Internal Medicine, Section Endocrinology, Erasmus Medical Center, 3015 GD Rotterdam, The Netherlands.
Article Synopsis
- Childhood cancer survivors (CCS) have a higher likelihood of developing dyslipidemia, which is a significant risk factor for heart disease, compared to adults without a cancer history.
- A study analyzed data from 2,338 CCS and found various lipid abnormalities in the survivors, indicating a prevalence of issues like high triglycerides and low HDL cholesterol.
- Factors influencing dyslipidemia in CCS included age, sex, BMI, physical activity, and treatment history, highlighting the need for tailored health monitoring for these individuals.
Metabolic syndrome among patients with type 2 diabetes in Jordan: A cross-sectional study.
Medicine (Baltimore)
November 2024
The National Center for Diabetes, Endocrinology, and Genetics, The University of Jordan, Amman, Jordan.
Metabolic syndrome is a major public health problem worldwide and an independent predictor of cardiovascular disease in patients with type 2 diabetes (T2DM). This study aimed to determine the prevalence of metabolic syndrome and its individual components among Jordanian patients with T2DM. A cross-sectional design was conducted among T2DM patients at the National Center for Diabetes, Endocrinology and Genetics in Jordan.
View Article and Find Full Text PDFMetabolic Syndrome in Psoriasis and Psoriatic Arthritis in a Mixed Race Population: Comparison of Their Prevalences.
Psoriasis (Auckl)
October 2024
Sector of Dermatology, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.
Background: There is a growing body of evidence suggesting the association between psoriasis (PsO) and psoriatic arthritis (PsA) separately with metabolic syndrome (MS) in different populations. The literature is relatively scarce in terms of comparing the prevalence of MS in PsO and PsA with controls without systemic inflammatory diseases.
Objective: We aimed to assess the prevalence of MS among patients with PsO, PsA, and a control group without systemic inflammatory disease, in addition to investigating the risks of MS occurrence and its different components in each group.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!