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Mediastinal Yolk Sac Tumor With Solitary Adenocarcinoma in Subcarinal Nodal Metastases.

Ann Thorac Surg Short Rep

March 2024

Division of Thoracic Surgery, Department of Surgery, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.

Germ cell tumors with somatic-type solid malignancy are mostly attributed to the malignant transformation of teratomas. Herein, we describe the case of a 41-year-old man with mediastinal yolk sac tumor who presented with adenocarcinoma in nodal metastases. Computed tomography revealed enlarged subcarinal lymph nodes and an anterior mediastinal tumor, which was diagnosed as a yolk sac tumor by percutaneous biopsy.

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This study aimed to determine the effects of the dietary Spirulina platensis supplementation and egg storage period on egg quality traits, blastoderm characteristics and hatching results of Mast geese. For this purpose, the control group was fed the standard enterprise diet, while the experimental group received the same diet supplemented with 0.5% S.

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Germ cell tumors in children.

Virchows Arch

January 2025

Department of Pathology and Laboratory Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.

Pediatric germ cell tumors represent a rare but biologically diverse group of neoplasms arising from pluripotent primordial germ cells. The 2022 edition of the WHO Classification of Pediatric Tumors introduced the first organ independent classification of germ cell tumors, reflecting advances in molecular biology, histopathology, and clinical practice. This review highlights the key changes, including the refined distinctions between the different subtypes.

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Divergent destinies: insights into the molecular mechanisms underlying EPI and PE fate determination.

Life Sci Alliance

March 2025

https://ror.org/05f950310 Department of Development and Regeneration, Stem Cell Institute, KU Leuven, Leuven, Belgium

Mammalian pre-implantation development is entirely devoted to the specification of extra-embryonic lineages, which are fundamental for embryo morphogenesis and support. The second fate decision is taken just before implantation, as defined by the epiblast (EPI) and the primitive endoderm (PE) specification. Later, EPI forms the embryo proper and PE contributes to the formation of the yolk sac.

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Extracranial and nonvaginal extragonadal malignant germ cell tumors: 12 cases at a Chinese institution over the last 38 years.

Arch Gynecol Obstet

January 2025

Department of Obstetrics and Gynecology, National Clinical Research Center for Obstetric & Gynecologic Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

Purpose: To provide a comprehensive understanding and propose a strategy for the management of extragonadal malignant germ cell tumors (EMGCTs) arising from extracranial and nonvaginal sites.

Methods: We retrospectively reviewed the cases of 12 patients with EMGCTs arising from extracranial and nonvaginal sites treated in our center over the past 38 years. Data on clinicopathological characteristics, treatment modalities, and follow-up information were analyzed.

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