A lot of treatment strategies available for diabetes but its complications are still a medical problem around the globe. It demands to find out some alternative therapeutic measures. In order to investigate the anti-diabetic potential of probiotics and natural extracts, this study was designed. Accordingly, a local source of yogurt probiotic strain Lactobacillus fermentum was isolated and characterized that showed its probiotic properties. Besides this, natural extracts of plants fruits like java plum (Syzygium cumini) and bitter gourd (M. charantia) were made. Lactobacillus fermentum and the extracts were administered individually as well as in combination to diabetes induced mice. Different parameters like body weight, blood glucose level and lipid profile including total cholesterol, HDL & LDL were analyzed before and after treatment. The results showed that Lactobacillus fermentum and natural extracts have hypoglycemic as well hypolipidemic activity against diabetic mice. This study can further investigated to screen potential compounds from these extracts to control the glucose and the lipid levels in diabetic patients.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Selection of GABA-Producing Lactic Acid Bacteria Strains by Polymerase Chain Reaction Using Novel B and C Multispecies Primers for the Development of New Functional Foods.
Int J Mol Sci
December 2024
Food Technology Department, National Institute for Agricultural and Food Research and Technology (INIA-CSIC), Carretera de La Coruña Km 7.5, 28040 Madrid, Spain.
Gamma-aminobutyric acid (GABA) has been attributed to health-promoting properties and has received attention from the food industry as an attractive bioactive compound for the development of functional foods. Some lactic acid bacteria (LAB) produce GABA through a glutamate decarboxylase encoded by B and a glutamate/GABA antiporter encoded by C. In this study, we develop a molecular screening method based on a polymerase chain reaction able to detect those genes in different LAB species through the use of novel multispecies primers.
View Article and Find Full Text PDFIn Vitro Screening of Bacterial Isolates From Dairy Products for Probiotic Properties and Other Health-Promoting Attributes.
Food Sci Nutr
December 2024
Paradise Scientific Company Ltd Dhaka Bangladesh.
The present research was aimed to isolate potential probiotic organisms from dairy products locally made in and around the Saurashtra region of Gujarat. A total of 224 colonies were screened for primary attributes. Based on the results, 70 isolates were carried further for secondary screening.
View Article and Find Full Text PDFPostbiotic metabolites derived from lactobacillus fermentum as potent antiproliferative bioresources on HeLa cells with promising biocompatibility.
BMC Complement Med Ther
December 2024
Biotechnology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Chemotherapy administrations for cervical malignancy possess a variety of unfavorable influences on the human body. Scientists are interested in microbial-derived biomolecules or postbiotics as an alternative therapeutic strategy in malignant patients. This research investigated the mechanisms related to the function of two potential postbiotic Lactobacillus isolates, Lactobacillus fermentum CH and L.
View Article and Find Full Text PDFLactobacillus fermentum MCC2760 attenuates neurobehavioral alterations induced by oxidized oils in rats.
Metab Brain Dis
December 2024
Dept. of Biochemistry, CSIR-Central Food Technological Research Institute, Mysore, 570020, India.
Article Synopsis
- Long-term consumption of oxidized deep-fried oils can negatively impact brain abilities, leading to issues like decreased memory and increased anxiety in rats.
- Probiotics, specifically Lactobacillus fermentum MCC2760, show potential in reversing these negative neurobehavioral effects caused by the heated oils.
- The study emphasizes the importance of dietary choices, suggesting that adding probiotics may help protect cognitive functions against the harm of oxidized oils.
Antiplasmodial Activity of Probiotic YZ01 in ANKA Infected BALB/c Mice.
J Trop Med
December 2024
ANSES, INRAE, Ecole Nationale Vétérinaire d'Alfort, UMR BIPAR, Laboratoire de Santé Animale, Maisons-Alfort F-94700, France.
Malaria remains a significant global health challenge, with the deadliest infections caused by . In light of the escalating drug resistance and the limited effectiveness of available vaccines, innovative treatment approaches are urgently needed. This study explores the potential of the probiotic YZ01, isolated from traditionally fermented kindirmo milk, to modify host responses to ANKA infection.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!