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Impaired Left Atrial Reserve Function in Heart Failure With Preserved Ejection Fraction.
Circ Cardiovasc Imaging
August 2024
Department of Cardiovascular Medicine (K.K., T.H., N.Y., H.S., F.M., A.N., Y.T., T.K., H.I., M.O.), Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan.
Background: Left atrial (LA) dysfunction is common in heart failure (HF) with preserved ejection fraction. However, data on the pathophysiologic impacts of impaired LA functional reserve remained limited. We sought to determine the association of abnormal LA dynamics during exercise with cardiovascular reserve, exercise capacity, and clinical outcomes.
View Article and Find Full Text PDFExercise Stress Echocardiography-Based Phenotyping of Heart Failure With Preserved Ejection Fraction.
J Am Soc Echocardiogr
August 2024
Department of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan. Electronic address:
Article Synopsis
- The study focuses on heart failure with preserved ejection fraction (HFpEF), aiming to improve classification by incorporating exercise assessments alongside clinical characteristics.
- A total of 265 HFpEF patients were tested through exercise stress echocardiography, leading to the identification of three distinct phenogroups based on various clinical and exercise-related parameters.
- The phenogroups revealed differences in cardiac function, exercise capacity, and prognosis, with two groups showing higher rates of mortality and heart failure events compared to the third group.
Stress Echocardiography: Another Hilltop, and It Is Better Than Ever.
J Am Coll Cardiol
November 2023
Heart Institute (InCor), School of Medicine, University of São Paulo, São Paulo, Brazil.
Exercise Stress Echocardiography of the Right Ventricle and Pulmonary Circulation.
J Am Coll Cardiol
November 2023
Institute of Clinical Physiology, National Research Council, Pisa, Italy. Electronic address:
Article Synopsis
- Exercise echocardiography is vital for evaluating the right ventricle and pulmonary circulation, but there's a need for clearer understanding of normal ranges and disease-specific variations.
- The study involved 2,228 participants including healthy individuals, athletes, and patients with different heart and lung conditions, who underwent echocardiography at rest and during exercise.
- Key findings indicate that certain measurements can predict increased mortality risk, highlighting significant differences in responses to exercise between healthy subjects and various patient groups.
Stressed Blood Volume in Severe Tricuspid Regurgitation: Implications for Transcatheter Treatment.
JACC Cardiovasc Interv
September 2023
Department of Cardiology, Heart Center at University of Leipzig and Leipzig Heart Institute, Leipzig, Germany.
Article Synopsis
- Tricuspid transcatheter edge-to-edge repair (TEER) can help patients with tricuspid regurgitation (TR), but many still face risks post-procedure, especially related to stressed blood volume (eSBV).
- A study of 279 patients found that eSBV is linked to factors like obesity and organ dysfunction, critically impacting heart failure and blood flow dynamics.
- Higher eSBV was associated with worse outcomes, such as persistent venous congestion after TEER and increased rates of death and hospitalizations for heart failure, suggesting the need for better patient screening for additional treatments.
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