AI Article Synopsis
- - The study investigates the effectiveness of capsule endoscopy (CE) as a diagnostic tool for patients with small bowel Crohn's disease (CD), comparing it to other diagnostic methods.
- - After reviewing 24 studies, it was found that CE has a higher diagnostic yield for suspected CD compared to small bowel follow-through and enteroclysis, but not compared to advanced imaging techniques like CT enterography or MR enterography.
- - The results suggest that CE is particularly effective for detecting lesions in the terminal ileum and is better than enteroclysis in evaluating both suspected and established cases of Crohn's disease.
Article Abstract
Background/aims: As a result of the rapid development of medical diagnostic tools, physicians require concrete evidence to evaluate the effectiveness of the tools. We aimed to investigate the effectiveness and additional diagnostic benefits of capsule endoscopy (CE) in patients with small bowel Crohn's disease (CD).
Methods: We performed a systematic search of databases, including MEDLINE, EMBASE, and the Cochrane Library, as well as eight domestic databases. Two reviewers independently screened all references. Diagnostic data from the studies were collected, and a meta-analysis was performed.
Results: Twenty-four studies were included. In cases of suspected CD, CE demonstrated a superior diagnostic yield compared with small bowel follow-through (SBFT) and enteroclysis (EC); however, there was no difference compared with computed tomography enterography or magnetic resonance enterography. In cases with established CD, CE demonstrated a higher diagnostic yield only compared with EC. In the detection of terminal ileum lesions, CE exhibited a significantly increased detection rate compared with ileoscopy.
Conclusions: The findings of our meta-analysis indicate that CE is superior to SBFT and EC in the evaluation of suspected CD cases. CE is also a more effective diagnostic modality in patients with established CD compared with EC.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221862 | PMC |
| http://dx.doi.org/10.5009/gnl16015 | DOI Listing |
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