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Generalized Seizure as an Acute post-Lu177-DOTATATE Side Effect in a Case of Recurrent Meningioma.
Cancer Biother Radiopharm
January 2025
Department of Nuclear Medicine, Namazi Hospital, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
[Lu]Lu-DOTATATE is a newly trending acceptable therapy in recurrent/residual meningioma with good safety. However, recognizing any possible side effects in this special population would be helpful for better management and individualization of this useful treatment. Although the seizure has been previously reported in a few cases after [Lu]Lu-DOTATATE therapy in recurrent meningioma, the acute onset of seizure in these patients, early after therapeutic radioligand administration, is not reported to the best of our knowledge.
View Article and Find Full Text PDFTranstuberculum approach to suprasellar meningioma with partial vessel encasement.
J Clin Neurosci
December 2024
Department of ENT, Head and Neck Surgery, Apollo Hospital, Chennai 600006, India. Electronic address:
Meningiomas in Rubinstein-Taybi syndrome: A case report and comprehensive review.
J Neuropathol Exp Neurol
December 2024
Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
Rubinstein-Taybi syndrome (RTS) is a congenital disorder with characteristic clinical manifestations. In the vast majority of cases, it is caused by mutations of the gene encoding the transcriptional co-activator cAMP-response element binding protein (CBP)-binding protein (CREBBP). It has been thought to be a tumor predisposition syndrome as RTS patients have an increased risk of developing tumors including meningiomas.
View Article and Find Full Text PDFPleomorphic dermal sarcoma of the scalp with intracranial space involvement: management of a rare entity. Illustrative case.
J Neurosurg Case Lessons
December 2024
Multidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania "Luigi Vanvitelli," Naples, Italy.
Background: Exophytic tumors of the calvaria (ETCs) remain a challenging pathology because of their complex management. The authors discuss the case of a woman with a large exophytic mass of the right frontotemporal region and underline their decision-making process on the management of this unique case and possible similar ones.
Observations: Neuroradiological findings showed a calvarial tumor with both epicranial and intracranial extension involving the frontotemporal bone with a mixed component (lytic and sclerotic) and dural infiltration with a pseudonodular pattern.
NF2 can mediate the expression of CAMK2A in a tissue specific manner.
Sci Rep
December 2024
College of Life Sciences, Zhejiang University, Zhejiang, 310058, China.
Meningioma is the most prevalent primary intracranial tumor, with approximately half of patients harboring NF2 alteration. The rationale behind the presence of NF2 alteration in meningiomas and its absence in non-nerve system tumors remains elusive. Therefore, meningiomas and several non-nerve system tumor types were analyzed using KEGG analysis and CRISPR/Cas 9 technology to determine the role of NF2 in regulating tissue specificity.
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