Epigenetic marks determine cell fate via numerous reader proteins. H3K36 methylation is a common epigenetic mark that is thought to be associated with the activities of the RNA polymerase 2 C-terminal domain. We discuss a novel silencing mechanism regulated by Set2-dependent H3K36 methylation that involves exosome-dependent RNA processing.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279713 | PMC |
http://dx.doi.org/10.1080/21541264.2016.1246076 | DOI Listing |
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