H3K36 methylation state and associated silencing mechanisms.

Transcription

a Department of Chemistry , Faculty of Science, Hokkaido University, Sapporo , Japan.

Published: January 2017

Epigenetic marks determine cell fate via numerous reader proteins. H3K36 methylation is a common epigenetic mark that is thought to be associated with the activities of the RNA polymerase 2 C-terminal domain. We discuss a novel silencing mechanism regulated by Set2-dependent H3K36 methylation that involves exosome-dependent RNA processing.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279713PMC
http://dx.doi.org/10.1080/21541264.2016.1246076DOI Listing

Publication Analysis

Top Keywords

h3k36 methylation
12
methylation state
4
state associated
4
associated silencing
4
silencing mechanisms
4
mechanisms epigenetic
4
epigenetic marks
4
marks determine
4
determine cell
4
cell fate
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!