Solitary Fibrous Tumor in the Lacrimal Gland Fossa: A Case Report.

Case Rep Ophthalmol

Department of Oculoplastic, Orbital and Lacrimal Surgery, Aichi Medical University Hospital, Aichi, Japan.

Published: September 2016

AI Article Synopsis

  • Solitary fibrous tumors (SFTs) are benign tumors typically found in the superior orbital area and can occur in young adults, as seen in this case of a 25-year-old woman.
  • A 6-month history of a painless mass in the left upper eyelid and proptosis led to imaging studies revealing a well-defined mass in the lacrimal gland region without affecting nearby bone.
  • Excision biopsy and immunohistochemical analysis confirmed the diagnosis of SFT with a positive result for signal transducer and activator of transcription 6.

Article Abstract

Solitary fibrous tumors (SFTs) are benign, spindle-cell tumors of mesenchymal origin that are usually seen in the superior orbital area in adults. We report a rare case of SFT in the lacrimal gland fossa that developed in a young female. A 25-year-old woman had a 6-month history of a progressive painless mass in the left upper eyelid accompanied by proptosis. Computed tomography and magnetic resonance imaging showed an ovoid, demarcated mass with distinct margins in the lacrimal gland region without bone invasion. Excision biopsy with immunohistochemical study, specifically with positive signal transducer and activator of transcription 6, confirmed the diagnosis.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043291PMC
http://dx.doi.org/10.1159/000448164DOI Listing

Publication Analysis

Top Keywords

lacrimal gland
12
solitary fibrous
8
gland fossa
8
fibrous tumor
4
tumor lacrimal
4
fossa case
4
case report
4
report solitary
4
fibrous tumors
4
tumors sfts
4

Similar Publications

Advances in lacrimal gland organoid development: Techniques and therapeutic applications.

Biomed Pharmacother

January 2025

Department of Stem Cell and Regenerative Biotechnology, School of Advanced Biotechnology, Molecular & Cellular Reprogramming Center, Institute of Advanced Regenerative Science, and Institute of Health, Aging & Society, Konkuk University, 120 Neungdong-ro Gwangjin-gu, Seoul 05029, Republic of Korea; R&D Team, StemExOne Co., Ltd., Seoul, Republic of Korea. Electronic address:

The human lacrimal gland (LG), located above the outer orbital region within the frontal bone socket, is essential in maintaining eye surface health and lubrication. It is firmly anchored to the orbital periosteum by the connective tissue, and it is vital for protecting and lubricating the eye by secreting lacrimal fluid. Disruption in the production, composition, or secretion of lacrimal fluid can lead to dry eye syndrome, a condition characterized by ocular discomfort and potential eye surface damage.

View Article and Find Full Text PDF

Assessing Facial Thermal Nociceptive Response in Female Dogs After Elective Ovariohysterectomy Anesthetized with Isoflurane and Treated with Cannabidiol and Meloxicam Analgesia.

Animals (Basel)

January 2025

Neurophysiology of Pain, Behavior and Assessment of Welfare in Domestic Animals, Department of Animal Production and Agriculture, Universidad Autónoma Metropolitana (UAM), Mexico City 04960, Mexico.

Pain management requires the identification of certain indicators to recognize pain. Various tools have been suggested to achieve an objective evaluation, including infrared thermography (IRT). The objective of this study was to assess the facial thermal nociceptive response produced by the use of cannabidiol (CBD) alone and in combination with meloxicam in female dogs undergoing elective ovariohysterectomy anesthetized with isoflurane.

View Article and Find Full Text PDF

Orbital and adnexal sarcoidosis: Clinical presentations and management outcomes.

Indian J Ophthalmol

February 2025

Department of Orbit, Oculoplasty, Reconstructive and Aesthetic Services, Sankara Nethralaya, Medical Research Foundation, Chennai, Tamil Nadu, India.

Purpose: To present the clinical features and management outcomes in a series of patients with orbital and adnexal sarcoidosis.

Methods: This was a retrospective analysis of 19 histopathologically proven cases of orbital and adnexal sarcoidosis over the past ten years. The data analyzed included demographic details, clinical and imaging features, and management outcomes.

View Article and Find Full Text PDF

Purpose: To evaluate the lacrimal punctal changes in different age groups using anterior segment optical coherence tomography (AS-OCT).

Methods: A cross-sectional observational study was conducted between January 2023 and January 2024 including healthy subjects between 20 and 80 years. The selected eyes from healthy patients were divided into four age groups (21-35 years, 36-50 years, 51-65 years, 66-80 years), and lower lacrimal puncta were analyzed using AS-OCT.

View Article and Find Full Text PDF

Application of S-100 absorbable hemostatic patch in endonasal endoscopic dacryocystorhinostomy: A randomized controlled trial.

Indian J Ophthalmol

February 2025

Hainan Eye Hospital and Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Haikou, Hainan Province, China.

Purpose: To investigate the effect of S-100 absorbable hemostatic patch coverage on anastomotic mucosa in endonasal endoscopic dacryocystorhinostomy (En-DCR).

Methods: Two hundred and twenty-six patients with unilateral chronic dacryocystitis (CD) were randomly divided into two groups in a randomized controlled trial: the S-100 absorbable hemostatic patch group (group A) and the control group (group B). All patients underwent En-DCR.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!