Oral isotretinoin has been in widespread use for more than three decades. It causes numerous side effects; skin and mucous membrane being commonly involved. Musculoskeletal adverse effects are also known to occur, but pelvic girdle myopathy is rarely reported. We report myopathy involving pelvic girdle muscles in a young male who received oral isotretinoin for folliculitis decalvans.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051260PMC
http://dx.doi.org/10.4103/0253-7613.190764DOI Listing

Publication Analysis

Top Keywords

pelvic girdle
12
myopathy involving
8
involving pelvic
8
girdle muscles
8
oral isotretinoin
8
isotretinoin-induced acute
4
acute severe
4
severe myopathy
4
muscles case
4
case report
4

Similar Publications

Introduction: Surgical treatment of pelvic girdle pain (PGP) involves arthrodesis of sacroiliac (SI) and pubic symphysis joints. Fusion of pubic symphysis involves the implantation of an autologous iliac crest tricortical graft harvested from the iliac crest. The objective was to assess the safety of a novel synthetic graft substitute (b.

View Article and Find Full Text PDF
Article Synopsis
  • This study examines how the growth and calcification of the appendicular skeleton in the Raja asterias affects its movement in water, highlighting the link between bone structure and fin mechanics.
  • It identifies two growth patterns—crustal in larger skeletal parts and catenated in fin radials—showing how differences in development can influence fin flexibility and locomotion.
  • The results suggest that unique calcification patterns, especially in the pelvic fins, evolve to meet the mechanical needs of swimming, emphasizing the adaptability of Batoidea fins through their joint structures and specialized designs.
View Article and Find Full Text PDF

During pregnancy, women undergo significant physiological, hormonal, and biomechanical changes that influence their gait. The forward shift of the center of mass and increased joint loads often result in a "waddling gait," elevating the risk of falls. While gait changes during pregnancy have been documented, findings across studies remain inconsistent, particularly regarding variations at different pregnancy stages.

View Article and Find Full Text PDF

Hodgkin Lymphoma As the Underlying Cause of a Chronic Cough.

Cureus

November 2024

Family Medicine, UCSP Paço de Arcos, Unidade Local de Saúde Lisboa Ocidental, Lisbon, PRT.

Hodgkin lymphoma (HL) is a monoclonal lymphoid neoplasm derived from B cells and is one of the most common lymphomas among young adults in developed countries. It typically presents insidiously, often as a painless cervical lymphadenopathy or an asymptomatic mediastinal mass. B symptoms (fever, night sweats, and weight loss), fatigue, pruritus, or alcohol-induced pain may be present along with respiratory symptoms in cases of mediastinal involvement.

View Article and Find Full Text PDF
Article Synopsis
  • Limb-girdle muscular dystrophy recessive 1 (LGMDR1) is a rare genetic muscle disorder caused by mutations in the CAPN3 gene, leading to progressive muscle weakness.
  • A case study of a 17-year-old boy with LGMDR1 revealed he developed a desmoplastic small round cell tumor (DSRCT), a rare and aggressive type of cancer, confirmed through molecular tests.
  • Despite thorough genetic testing, no known childhood cancer predisposition genes were found, highlighting the need for more research into the potential cancer risks associated with LGMDR1.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!