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Predictive accuracy of the complex 30-day model for colon surgical site infections in emergent operations.
Am J Surg
March 2025
Division of Surgical Oncology, Department of Surgery, Brody School of Medicine at East Carolina University, Greenville, NC, USA. Electronic address:
Background: Surgical site infections (SSI) following colon surgery continue to pose a significant clinical and financial impact on a healthcare system. The National Healthcare Safety Network (NHSN) utilizes the Complex 30-day SSI model to report the predictive number of infections for a hospital, which is submitted to the Centers for Medicare and Medicaid Services. However, this model does not account for patient acuity.
View Article and Find Full Text PDFMitochondria Isolated From Bone Mesenchymal Stem Cells Restrain Muscle Disuse Atrophy and Fatty Infiltration After Rotator Cuff Tears.
Am J Sports Med
March 2025
Division of Joint Surgery and Sports Medicine, Department of Orthopedic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.
Background: Rotator cuff tears (RCTs) commonly lead to muscle atrophy, fibrosis, and fatty infiltration, complicating treatment.
Purpose: To investigate the use of mitochondria isolated from bone mesenchymal stem cells (BMSC-Mito) for mitigating complications after RCT, focusing on muscle protection.
Study Design: Controlled laboratory study.
Civilian death and injury from airstrikes: evidence from the war in Tigray, Ethiopia.
Popul Health Metr
March 2025
Department of Surgery, University of Washington, Seattle, WA, USA.
Background: Civilians bear a significant burden of morbidity and mortality in modern armed conflicts, particularly when explosive weapons are used in densely populated areas. Many civilian facilities were attacked in the war in Tigray since the beginning of hostilities in November 2020. This study assessed the impact of airstrikes on civilians from June 2021 until the signing of the Agreement for Lasting Peace through a Permanent Cessation of Hostilities between the Ethiopian Government and the Tigray People's Liberation Front in November 2022.
View Article and Find Full Text PDFTraumatic Brain Injury and Gut Microbiome: The Role of the Gut-Brain Axis in Neurodegenerative Processes.
Curr Neurol Neurosci Rep
March 2025
Department of Neurology, University of New Mexico, MSC10-5620, Albuquerque, NM, 87131, USA.
Purpose Of Review: A deeper understanding of the communication network between the gut microbiome and the central nervous system, termed the gut-brain axis (GBA), has revealed new potential targets for intervention to prevent the development of neurodegenerative disease associated with tramatic brain injury (TBI). This review aims to comprehensively examine the role of GBA post-traumatic brain injury (TBI).
Recent Findings: The GBA functions through neural, metabolic, immune, and endocrine systems, creating bidirectional signaling pathways that modulate brain and gastrointestinal (GI) tract physiology.
"Improving postnatal maternity care following severe perineal trauma by evaluating end-user's experiences of a pilot trial exploring laxative management; A qualitative study".
Appl Nurs Res
April 2025
Division of Surgical Specialties & Anaesthesia, Northern Adelaide Local Health Network, Haydown Rd Elizabeth Vale, South Australia, Australia; Adjunct Associate Professor Flinders University, University Dr Bedford Park, South Australia, Australia; Affiliated Flinders University Caring Futures Institute, University Dr Flinders University Bedford Park, South Australia, Australia; Adjunct Industry Fellow University of South Australia, North Terrace, Adelaide, South Australia, Australia. Electronic address:
Background: Trauma to the anal sphincter following vaginal birth increases the risk of anal incontinence. Laxative management in the postnatal period is recommended to improve defecation and reduce the risk of wound breakdown. Research underpinning management guidelines is lacking and omits end-users (clinicians and birthing women) involvement in evaluating pilot studies.
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