[Biochemical bases of adverse reactions to antibacterial preparations used in renal tuberculosis and means of their prevention].

Factors leading to development of adverse reactions to antituberculous drugs in patients with nephrophthisis were studied and complex treatment regimens to prevent the reactions were developed. The use of such regimens along with chemotherapy allowed the frequency of adverse reactions to be lowered almost 2-fold in patients with limited nephrophthises and to postpone the development of adverse reactions in patients with extended tuberculosis for 1-1.5 months.